COF-RYL Cough Syrup

Introduction

COF-RYL Cough is a prescription medication that contains Diphenhydramine, Ammonium Chloride, and Sodium Citrate as its active ingredients. It is available in syrup form and is commonly marketed under the brand name COF-RYL Cough. This medication is primarily used to provide temporary relief from cough associated with respiratory tract infections.

Uses

COF-RYL Cough is prescribed to help alleviate cough caused by various respiratory tract infections, such as the common cold, bronchitis, and asthma. It works by reducing irritation in the throat and airways, helping to suppress coughing and promoting a more comfortable breathing experience.

Dosage and Administration

follow the dosage instructions provided by your healthcare professional or as indicated on the product packaging. The usual recommended dosage for adults and children over 12 years old is 10 ml (2 teaspoons) of COF-RYL Cough, taken three to four times a day. For children between 6 and 12 years old, the recommended dosage is 5 ml (1 teaspoon) three to four times a day. Please note that dosages may vary depending on the severity of the cough and the individual’s response to treatment.

COF-RYL Cough should be taken orally, preferably with food, to minimize the risk of stomach upset. Use the provided measuring device to ensure accurate dosing. Shake the syrup well before each use.

Mechanism of Action

Diphenhydramine, one of the active ingredients in COF-RYL Cough, is an antihistamine that works by blocking the effects of histamine, a substance in the body that is involved in allergic reactions and cough reflexes. By reducing the activity of histamine, Diphenhydramine helps to relieve cough and associated symptoms.

Ammonium Chloride and Sodium Citrate, the other active ingredients in COF-RYL Cough, work by thinning and loosening mucus in the airways, making it easier to cough out and clear the respiratory passages.

Side Effects

Common side effects may include drowsiness, dizziness, dry mouth, and blurred vision. These side effects are usually mild and transient.

However, if you experience any of the following serious side effects, please seek immediate medical attention:

• Allergic reactions: Symptoms may include rash, itching, swelling, severe dizziness, or difficulty breathing.
• Irregular heartbeat or palpitations: If you notice any changes in your heart rate or rhythm. Consult a healthcare professional.
• Severe drowsiness or confusion: If you feel excessively drowsy or confused, especially to the point of impairment, seek medical help.

Note that this is not an exhaustive list of side effects. If you experience any other unusual or persistent symptoms, please consult your healthcare provider.

Drug Interactions

Before taking COF-RYL Cough, inform your healthcare provider about all other medications you are taking, including prescription, over-the-counter, and herbal products. Some medications may interact with COF-RYL Cough and potentially increase the risk of side effects or reduce the effectiveness of either medication.

Common drug interactions may include:

• Monoamine oxidase inhibitors (MAOIs): Combining COF-RYL Cough with MAOIs may increase the risk of serious side effects, such as high blood pressure or seizures.
• Sedatives or tranquilizers: Taking COF-RYL Cough with sedatives or tranquilizers may enhance the sedative effects of both medications, leading to excessive drowsiness or impairment.

This is not an exhaustive list of drug interactions. Consult your healthcare provider or pharmacist for a complete list of potential interactions.

Precautions

Before using COF-RYL Cough, inform your healthcare provider about any allergies you may have, as well as your medical history, especially if you have a history of asthma, glaucoma, urinary retention, or liver disease.

Certain precautions and contraindications apply to the use of COF-RYL Cough. It should not be used in children under 6 years old, unless specifically prescribed by a healthcare professional. Additionally, COF-RYL Cough should be used with caution in elderly individuals, as they may be more susceptible to the medication’s side effects, such as drowsiness and dizziness.

Avoid consuming alcohol while taking COF-RYL Cough, as it may increase the risk of drowsiness and impair your ability to perform tasks that require alertness, such as driving or operating machinery.

Storage

COF-RYL Cough should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use the syrup if it has expired or if you notice any changes in its appearance or odor. Proper storage helps to maintain the effectiveness and safety of the medication.

Patient Tips

To ensure the safe and effective use of COF-RYL Cough, consider the following patient tips:

• Follow the recommended dosage: Take the medication as prescribed by your healthcare professional or as directed on the product packaging. Do not exceed the recommended dosage unless advised by your healthcare provider.
• Drink plenty of fluids: Staying hydrated can help to thin and loosen mucus in the airways, making it easier to clear.
• Avoid irritants: Try to minimize exposure to irritants, such as smoke and strong odors, as they can worsen cough symptoms.
• Rest and maintain good hygiene: Adequate rest and proper hygiene practices, such as covering your mouth and nose when coughing or sneezing, can help prevent the spread of respiratory infections.
• Consult your healthcare provider: If your symptoms worsen or persist despite using COF-RYL Cough, consult your healthcare provider for further evaluation and management.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Vitamins and minerals – Others (NHS UK) [Accessed 18 Jun. 2024] (online) Available at:
• Benylin Chesty Coughs (Original) (Health Professionals SmPC) Available at:
• Ammonium Chloride (Drugs.com) [Accessed 16 Jun. 2024] (online) Available at:
• allergy cream (diphenhydramine, zinc) 2 %-0.1 % topical (OTC) [Accessed 18 Jun. 2024] (online) Available at:
• Acid loading test (pH) [Accessed 16 Jun. 2024] (online) Available at:
• [No authors listed] Ammonium chloride acidosis. Br Med J. 1961 Aug 12;2(5249):441. [Accessed 3 Jun. 2024] Available at: