Comantrel 100 Capsule

Introduction

Comantrel is a prescription medication that contains the active ingredient Amantadine. It is available under the brand name Comantrel. This medication is primarily used for the treatment of Parkinson’s disease, a neurodegenerative disorder that affects movement and muscle control.

Uses

Comantrel is prescribed to alleviate the symptoms of Parkinson’s disease, including tremors, stiffness, and difficulties with movement. It helps to restore the balance of certain chemicals in the brain, which can improve muscle control and reduce the severity of symptoms.

Dosage and Administration

The dosage of Comantrel will vary depending on individual patient factors, such as the severity of symptoms and response to treatment. Follow the instructions provided by your healthcare professional. Generally, the recommended starting dose for adults is 100 mg per day, taken in divided doses. The dosage may be gradually increased under medical supervision. It is typically taken orally with or without food.

Mechanism of Action

Comantrel works by increasing the levels of dopamine in the brain. Dopamine is a neurotransmitter that plays a key role in regulating movement and muscle control. By enhancing dopamine activity, Amantadine helps to improve motor symptoms associated with Parkinson’s disease.

Side Effects

Common side effects may include nausea, dizziness, dry mouth, constipation, and insomnia. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, consult your healthcare professional.

In rare cases, Comantrel may cause more serious side effects. These can include hallucinations, confusion, difficulty urinating, swelling of the feet or ankles, and shortness of breath. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all medications you are currently taking, including prescription, over-the-counter, and herbal products. Comantrel may interact with certain medications, such as anticholinergic drugs, which can increase the risk of side effects. Additionally, medications that affect the central nervous system, such as sedatives or alcohol, may enhance the sedative effects of Comantrel. Your healthcare professional will assess the potential interactions and adjust your treatment plan accordingly.

Precautions

Before starting Comantrel, inform your healthcare professional about any medical conditions you have, especially if you have a history of seizures, heart problems, kidney disease, or liver disease. This medication may not be suitable for everyone, and your healthcare professional will evaluate the potential risks and benefits of treatment.

Comantrel is contraindicated in individuals who are allergic to Amantadine or any other ingredients in the formulation. Avoid abrupt discontinuation of the medication, as this may lead to withdrawal symptoms.

Storage

Comantrel should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Comantrel exactly as prescribed by your healthcare professional. Do not exceed the recommended dosage or stop taking the medication without consulting your healthcare professional.
• It may take some time for the full benefits of Comantrel to be experienced. Be patient and continue taking the medication as directed.
• If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• To help prevent constipation, drink plenty of fluids and maintain a healthy diet with adequate fiber.
• Avoid driving or operating machinery if you experience dizziness or drowsiness while taking Comantrel.
• If you have any concerns or questions about your treatment, consult your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Restless legs syndrome – Causes (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
• Amantadine 50mg/5mL oral solution (Health Professionals SmPC) Available at:
• Amantadine (Drugs.com) [Accessed 11 Jun. 2024] (online) Available at:
• amantadine (RX) [Accessed 19 Jun. 2024] (online) Available at:
• Amantadine (MedlinePlus) [Accessed 15 Jun. 2024] (online) Available at:
• Ma HM, Zafonte RD. Amantadine and memantine: a comprehensive review for acquired brain injury. Brain Inj. 2020 Feb 23;34(3):299-315. doi: 10.1080/02699052.2020.1723697. Epub 2020 Feb 20. [Accessed 20 Jun. 2024] Available at: