Corpril ST 5mg/10mg Tablet

Introduction

Corpril ST is a prescription medication that combines two active ingredients, Ramipril and Atorvastatin, to provide a comprehensive treatment option for certain cardiovascular conditions. Ramipril belongs to a class of drugs called ACE inhibitors, while Atorvastatin is a statin medication. Together, they work synergistically to help manage specific cardiovascular conditions.

Uses

Corpril ST is primarily prescribed for the management of hypertension (high blood pressure) and hyperlipidemia (high cholesterol levels). It is often recommended for patients who require treatment for both conditions simultaneously. By lowering blood pressure and reducing cholesterol levels, Corpril ST helps decrease the risk of cardiovascular events such as heart attacks and strokes.

Dosage and Administration

Corpril ST should be taken as directed by your healthcare provider. The dosage may vary depending on your specific medical condition and individual response to the medication. It is usually taken once daily, with or without food. Swallow the tablet whole with a glass of water, and do not crush or chew it.

Mechanism of Action

Ramipril, one of the active ingredients in Corpril ST, works by inhibiting the action of an enzyme called angiotensin-converting enzyme (ACE). This leads to the relaxation of blood vessels, resulting in a reduction in blood pressure. Atorvastatin, on the other hand, works by inhibiting the production of cholesterol in the liver, thus lowering the levels of “bad” cholesterol (LDL) in the bloodstream. By targeting both blood pressure and cholesterol levels, Corpril ST provides comprehensive cardiovascular protection.

Side Effects

Common side effects may include headache, dizziness, cough, fatigue, and gastrointestinal symptoms such as nausea or diarrhea. These side effects are generally mild and temporary.

However, be aware of potential serious side effects that may require immediate medical attention. These can include symptoms such as severe allergic reactions, swelling of the face or throat, difficulty breathing, chest pain, or signs of liver problems such as jaundice (yellowing of the skin or eyes), dark urine, or persistent abdominal pain. If you experience any of these serious side effects, seek medical help right away.

Drug Interactions

Corpril ST may interact with certain medications, including other blood pressure-lowering drugs, diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain antibiotics. These interactions can affect the effectiveness of the medications or increase the risk of side effects. Inform your healthcare provider about all the medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

Precautions

Before taking Corpril ST, inform your healthcare provider about any existing medical conditions you may have, especially if you have a history of liver or kidney disease, diabetes, or if you are pregnant or breastfeeding. Corpril ST may not be suitable for everyone, and your healthcare provider will assess the potential risks and benefits before prescribing it to you.

Additionally, avoid consuming excessive amounts of alcohol while taking Corpril ST, as it may increase the risk of liver problems. It is also advisable to avoid grapefruit or grapefruit juice, as it may interact with Atorvastatin and affect its effectiveness.

Storage

Corpril ST should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use Corpril ST beyond its expiration date, which is printed on the packaging.

Patient Tips

• Take Corpril ST exactly as prescribed by your healthcare provider. Do not alter the dosage or stop taking the medication without consulting your doctor.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
• Maintain a healthy lifestyle by following a balanced diet, engaging in regular exercise, and avoiding smoking or excessive alcohol consumption. These lifestyle modifications can complement the effectiveness of Corpril ST in managing your cardiovascular health.
• Attend regular check-ups with your healthcare provider to monitor your blood pressure and cholesterol levels, and to assess your response to Corpril ST.
• If you experience any unusual symptoms or have concerns about the medication, do not hesitate to reach out to your healthcare provider for guidance and support. They are the best resource for addressing your specific needs and ensuring your overall well-being.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Atorvastatin: a medicine to treat high blood cholestesterol (NHS UK) [Accessed 5 Jun. 2024] (online) Available at:
• Atorvastatin 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Atorvastatin (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• atorvastatin (RX) [Accessed 21 Jun. 2024] (online) Available at:
• Atorvastatin (MedlinePlus) [Accessed 1 Jun. 2024] (online) Available at:
• Yu L, Liu S, Zhou R, Sun H, Su X, Liu Q, Li S, Ying J, Zhao F, Mu D, Qu Y. Atorvastatin inhibits neuronal apoptosis via activating cAMP/PKA/p-CREB/BDNF pathway in hypoxic-ischemic neonatal rats. FASEB J. 2022 Apr;36(4):e22263. doi: 10.1096/fj.202101654RR. [Accessed 15 Jun. 2024] Available at: