Crizalk 200mg Capsule

Introduction

Crizalk is a prescription medication that contains the active ingredient Crizotinib. It is available in the form of capsules and is used for the treatment of certain types of cancer.

Uses

Crizalk is primarily prescribed for the treatment of non-small cell lung cancer that is caused by a specific genetic mutation known as anaplastic lymphoma kinase (ALK). It is also used for the treatment of certain types of metastatic non-small cell lung cancer.

Dosage and Administration

The dosage of Crizalk may vary depending on individual factors such as the patient’s weight, overall health, and response to treatment. Follow the instructions provided by your healthcare professional. The capsules should be taken orally with or without food, as directed.

Mechanism of Action

Crizotinib, the active ingredient in Crizalk, works by inhibiting the activity of certain proteins that are involved in the growth and spread of cancer cells. It specifically targets and blocks the activity of the anaplastic lymphoma kinase (ALK) protein, which is found in some cancer cells. By inhibiting this protein, Crizotinib helps to slow down or stop the growth of cancer cells.

Side Effects

Common side effects may include nausea, diarrhea, fatigue, constipation, and changes in appetite. Report any persistent or bothersome side effects to your healthcare professional.

Serious side effects may occur in rare cases and may include lung problems, liver problems, heart problems, and vision changes. If you experience any unusual symptoms or side effects, such as difficulty breathing, yellowing of the skin or eyes, chest pain, or sudden changes in vision, seek immediate medical attention.

Drug Interactions

Crizalk may interact with other medications, including certain antibiotics, antifungal medications, and certain antidepressants. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, supplements, and herbal products.

Precautions

Before starting treatment with Crizalk, discuss your medical history and any pre-existing conditions with your healthcare professional. Inform them if you have any liver or kidney problems, heart disease, lung disease, or any other significant medical conditions.

Crizalk should not be used during pregnancy or while breastfeeding, as it may harm the unborn baby or pass into breast milk. Use effective contraception during treatment and for a period of time after stopping the medication, as advised by your healthcare professional.

Storage

Crizalk should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and do not change the dose without consulting them.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• attend all scheduled appointments with your healthcare professional for monitoring and evaluation of your treatment.
• Inform your healthcare professional about any other medications, supplements, or herbal products you are taking before starting treatment with Crizalk.
• If you experience any new or worsening symptoms during treatment, contact your healthcare professional immediately.
• Store the medication in its original packaging and discard any unused capsules as directed by your healthcare professional.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Xalkori 200 mg hard capsules (Health Professionals SmPC) Available at:
• Crizotinib (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• crizotinib capsule (RX) [Accessed 15 Jun. 2024] (online) Available at:
• Crizotinib (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
• Shaw AT, Bauer TM, de Marinis F, Felip E, Goto Y, Liu G, Mazieres J, Kim DW, Mok T, Polli A, Thurm H, Calella AM, Peltz G, Solomon BJ; CROWN Trial Investigators. First-Line Lorlatinib or Crizotinib in Advanced ALK-Positive Lung Cancer. N Engl J Med. 2020 Nov 19;383(21):2018-2029. doi: 10.1056/NEJMoa2027187. [Accessed 26 Jun. 2024] Available at: