Introduction
Cyramza is a prescription medication that contains the active ingredient Ramucirumab. It is available under the brand name Cyramza. This medication is primarily used in the treatment of certain types of cancer.
Uses
Cyramza is prescribed for the treatment of advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma. It is also used for the treatment of non-small cell lung cancer (NSCLC) and metastatic colorectal cancer (mCRC) when used in combination with other medications.
Dosage and Administration
Cyramza should only be administered by a healthcare professional. The dosage and administration schedule may vary depending on the specific cancer being treated and other individual factors. It is typically given as an intravenous infusion over a specified period of time. Your healthcare provider will determine the appropriate dosage and schedule for your condition.
Mechanism of Action
Ramucirumab, the active ingredient in Cyramza, is a monoclonal antibody that works by blocking the growth of new blood vessels in tumors. This helps to inhibit the growth and spread of cancer cells.
Side Effects
Common side effects may include high blood pressure, fatigue, diarrhea, decreased appetite, and nausea. Report any side effects to your healthcare provider.
Serious side effects may occur, although they are less common. These can include bleeding, blood clots, gastrointestinal perforation, and impaired wound healing. If you experience any severe or persistent side effects, seek medical attention immediately.
Drug Interactions
Cyramza may interact with other medications. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may increase the risk of side effects or reduce the effectiveness of Cyramza.
Precautions
Before using Cyramza, discuss your medical history and any pre-existing conditions with your healthcare provider. This medication may not be suitable for everyone, especially those with a history of bleeding disorders or certain heart conditions.
Cyramza should not be used during pregnancy unless clearly indicated by your healthcare provider. Use effective contraception during treatment and for a period of time after discontinuing the medication.
Storage
Patient Tips
- Attend all scheduled appointments with your healthcare provider for the administration of Cyramza.
- Be aware of the potential side effects of the medication and report any changes or concerns to your healthcare provider.
- Follow any dietary or lifestyle recommendations provided by your healthcare provider to optimize the effectiveness of the treatment.
- Store the medication properly according to the instructions to maintain its potency and stability.
- Do not alter the dosage or frequency of administration without consulting your healthcare provider.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Ramucirumab (Drugs.com) [Accessed 11 Jun. 2024] (online) Available at:
- ramucirumab solution (RX) [Accessed 1 Jun. 2024] (online) Available at:
- Ramucirumab Injection (MedlinePlus) [Accessed 28 Jun. 2024] (online) Available at:
- Garon EB, Ciuleanu TE, Arrieta O, Prabhash K, Syrigos KN, Goksel T, Park K, Gorbunova V, Kowalyszyn RD, Pikiel J, Czyzewicz G, Orlov SV, Lewanski CR, Thomas M, Bidoli P, Dakhil S, Gans S, Kim JH, Grigorescu A, Karaseva N, Reck M, Cappuzzo F, Alexandris E, Sashegyi A, Yurasov S, Pérol M. Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicentre, double-blind, randomised phase 3 trial. Lancet. 2014 Aug 23;384(9944):665-73. doi: 10.1016/S0140-6736(14)60845-X. Epub 2014 Jun 2. [Accessed 22 Jun. 2024] Available at:
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