Introduction
Dabica is a prescription medication that contains the active ingredient Dabigatran Etexilate. It is available in tablet form and is primarily used for the treatment and prevention of blood clots in patients with certain medical conditions.
Uses
Dabica is prescribed to patients who have undergone hip or knee replacement surgery to reduce the risk of blood clots. It is also used to prevent strokes and blood clots in patients with atrial fibrillation, a type of irregular heartbeat.
Dosage and Administration
The dosage of Dabica may vary depending on the specific condition being treated and the patient’s medical history. Follow the instructions provided by your healthcare provider. Typically, the recommended dose is 150 mg taken orally twice daily. The tablets should be swallowed whole with a glass of water, with or without food. Do not crush, chew, or break the tablets unless instructed otherwise.
Mechanism of Action
Dabica belongs to a class of medications called direct thrombin inhibitors. It works by inhibiting the action of thrombin, an enzyme involved in the formation of blood clots. By blocking thrombin, Dabica helps prevent the formation of new blood clots and reduces the risk of stroke and other clot-related complications.
Side Effects
Common side effects may include indigestion, nausea, stomach pain, and diarrhea. These side effects are usually mild and go away on their own. However, if you experience any severe or persistent side effects, such as unusual bleeding, black or tarry stools, or signs of an allergic reaction (e.g., rash, itching, swelling), seek medical attention immediately.
Drug Interactions
Dabica may interact with certain medications, including other blood thinners, antiplatelet drugs, and nonsteroidal anti-inflammatory drugs (NSAIDs). These interactions can increase the risk of bleeding or other complications. Inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.
Precautions
Before taking Dabica, inform your healthcare provider about any medical conditions you have, especially if you have a bleeding disorder, liver or kidney disease, or a history of stomach ulcers. Dabica should be used with caution in patients at increased risk of bleeding. Avoid activities that may increase the risk of bleeding, such as contact sports or heavy lifting.
Storage
Patient Tips
- Take Dabica exactly as prescribed by your healthcare provider. Do not change the dose or stop taking the medication without consulting your doctor.
- If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
- attend regular follow-up appointments with your healthcare provider to monitor your response to the medication and check for any potential side effects or complications.
- Inform all healthcare professionals involved in your care, including dentists and surgeons, that you are taking Dabica as it may increase the risk of bleeding during certain procedures.
- Avoid taking other medications, including over-the-counter drugs and herbal supplements, without consulting your healthcare provider first, as they may interact with Dabica.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Dabigatran: medicine to help prevent blood clots (NHS UK) [Accessed 25 Jun. 2024] (online) Available at:
- Pradaxa 110 mg coated granules (Health Professionals SmPC) Available at:
- Dabigatran (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
- dabigatran etexilate 150 mg capsule thrombin inhibitors (non-heparinoid) (RX) [Accessed 0 Jun. 2024] (online) Available at:
- Paik J. Dabigatran Etexilate: A Review in Pediatric Venous Thromboembolism. Paediatr Drugs. 2022 Jul;24(4):423-431. doi: 10.1007/s40272-022-00516-z. Epub 2022 Jun 14. [Accessed 10 Jun. 2024] Available at:
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