Introduction
Dajio L is a prescription medication that contains two active ingredients: Dapagliflozin and Linagliptin. Dapagliflozin belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors, while Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. This combination medication is commonly prescribed to help control blood sugar levels in adults with type 2 diabetes mellitus.
Uses
Dajio L is primarily used to help lower blood sugar levels in adults with type 2 diabetes mellitus. It is often prescribed as an adjunct to diet and exercise to improve glycemic control. This medication may be prescribed alone or in combination with other antidiabetic medications, such as metformin or sulfonylureas.
Dosage and Administration
The recommended dosage of Dajio L may vary depending on individual factors, such as the patient’s overall health and response to treatment. Follow the dosage instructions provided by your healthcare provider. Typically, the recommended starting dose is one tablet taken orally once daily. The tablet can be taken with or without food. Take the medication as prescribed and not to exceed the recommended dose.
Mechanism of Action
Dajio L works by targeting two different mechanisms to help lower blood sugar levels. Dapagliflozin works by inhibiting SGLT2 in the kidneys, which reduces the reabsorption of glucose and leads to increased urinary glucose excretion. This helps to lower blood glucose levels. Linagliptin, on the other hand, works by inhibiting DPP-4, an enzyme that breaks down incretin hormones. By inhibiting DPP-4, Linagliptin helps to increase the levels of active incretin hormones in the body, which in turn stimulates insulin release and reduces the production of glucose by the liver.
Side Effects
Common side effects may include urinary tract infections, genital yeast infections, increased urination, thirst, and low blood sugar levels (hypoglycemia). Be aware of the signs and symptoms of hypoglycemia, such as sweating, trembling, dizziness, and confusion. If any side effects persist or worsen, or if you experience any serious side effects such as severe allergic reactions or signs of ketoacidosis (e.g., nausea, vomiting, stomach pain, fruity breath odor), seek medical attention immediately.
Drug Interactions
Dajio L may interact with certain medications, including diuretics, insulin or insulin secretagogues, and medications that affect blood glucose levels. Inform your healthcare provider about all the medications you are currently taking, including prescription medications, over-the-counter drugs, and herbal supplements, to avoid potential drug interactions.
Precautions
Before starting Dajio L, inform your healthcare provider about any pre-existing medical conditions, including kidney problems, liver disease, heart disease, and any allergies you may have. This medication may not be suitable for individuals with certain medical conditions or those who are pregnant or breastfeeding. Follow your healthcare provider’s instructions and precautions.
Storage
Dajio L should be stored at room temperature, away from moisture and heat. Keep this medication out of reach of children and pets. Do not use this medication if the packaging is damaged or if the expiration date has passed. Properly dispose of any unused or expired medication.
Patient Tips
- Take Dajio L exactly as prescribed by your healthcare provider.
- Follow a healthy diet and exercise routine while taking this medication to help manage your blood sugar levels.
- Monitor your blood sugar levels regularly as directed by your healthcare provider.
- Stay hydrated and drink plenty of water while taking Dajio L.
- If you forget to take a dose of Dajio L, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- If you have any questions or concerns about this medication, consult your healthcare provider for further guidance.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- About dapagliflozin (NHS UK) [Accessed 1 Jun. 2024] (online) Available at:
- Forxiga 10 mg film-coated tablets (Health Professionals SmPC) Available at:
- Dapagliflozin (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
- dapagliflozin propaned 10 mg-metformin er 1,000 mg tablet,ext rel 24hr antihyperglycemic-sod/gluc cotransport-2 (sglt2) inhibitors (RX) [Accessed 23 Jun. 2024] (online) Available at:
- Dapagliflozin (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
- Dhillon S. Dapagliflozin: A Review in Type 2 Diabetes. Drugs. 2019 Jul;79(10):1135-1146. doi: 10.1007/s40265-019-01148-3. [Accessed 15 Jun. 2024] Available at:
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