Introduction
Daruvir is a prescription medication that contains two active ingredients: Darunavir and Ritonavir. Darunavir belongs to a class of drugs known as protease inhibitors, while Ritonavir is a type of medication called a pharmacokinetic enhancer. Daruvir is commonly used in the treatment of human immunodeficiency virus (HIV) infection.
Uses
Daruvir is primarily prescribed to manage HIV infection in adults. It is used in combination with other antiretroviral medications to control the virus and improve immune function. This medication helps to reduce the amount of HIV in the bloodstream and slow down the progression of the disease.
Dosage and Administration
The dosage of Daruvir will vary depending on individual factors such as the patient’s weight, other medications being taken, and the stage of HIV infection. Follow the specific instructions provided by your healthcare professional. Generally, Daruvir is taken orally with food.
Mechanism of Action
Darunavir, one of the active ingredients in Daruvir, works by inhibiting the activity of the protease enzyme in HIV-infected cells. This prevents the virus from multiplying and infecting other healthy cells. Ritonavir, the other active ingredient, acts as a booster to increase the levels of Darunavir in the bloodstream, enhancing its effectiveness.
Side Effects
Common side effects may include nausea, diarrhea, headache, and fatigue. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, seek medical attention.
Serious side effects may include liver problems, pancreatitis, allergic reactions, and changes in heart rhythm. If you experience any signs of these serious side effects, such as yellowing of the skin or eyes, severe abdominal pain, difficulty breathing, or irregular heartbeat, seek immediate medical attention.
Drug Interactions
Daruvir may interact with other medications, including certain antiviral drugs, antibiotics, antifungal medications, and some herbal supplements. These interactions can affect the effectiveness of Daruvir or increase the risk of side effects. Inform your healthcare professional about all the medications you are taking before starting Daruvir.
Precautions
Before taking Daruvir, inform your healthcare professional about any known allergies or medical conditions you have. This medication may not be suitable for everyone, especially individuals with severe liver or kidney problems. Daruvir may also interact with certain medications, such as certain cholesterol-lowering drugs and blood thinners.
Storage
Daruvir should be stored at room temperature, away from moisture and heat. Keep the medication in its original packaging and out of reach of children. Do not use Daruvir if the expiration date has passed.
Patient Tips
- Take Daruvir exactly as prescribed by your healthcare professional. Do not skip doses or stop taking the medication without consulting your doctor.
- maintain a regular schedule for taking Daruvir to maximize its effectiveness.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not take a double dose to make up for a missed one.
- If you have any questions or concerns about Daruvir or its use, speak to your healthcare professional for further guidance.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Taking Paxlovid with other medicines and herbal supplements (NHS UK) [Accessed 9 Jun. 2024] (online) Available at:
- Darunavir 400 mg film-coated tablets (Health Professionals SmPC) Available at:
- Darunavir (Drugs.com) [Accessed 25 Jun. 2024] (online) Available at:
- darunavir ethanolate 800 mg tablet antiviral-hiv boosted protease inhibitors (RX) [Accessed 22 Jun. 2024] (online) Available at:
- Darunavir, Cobicistat, Emtricitabine, and Tenofovir (MedlinePlus) [Accessed 25 Jun. 2024] (online) Available at:
- Darwish IA, Al-Majed AA, Alsaif NA, Bakheit AH, Herqash RN, Alzaid A. Darunavir: A comprehensive profile. Profiles Drug Subst Excip Relat Methodol. 2021;46:1-50. doi: 10.1016/bs.podrm.2020.07.001. Epub 2020 Aug 21. [Accessed 2 Jun. 2024] Available at:
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