Deburrow 5% Lotion

Introduction

Deburrow is a topical medication that contains the active ingredient Permethrin. It is commonly known by its generic name, Permethrin, and is available under the brand name Deburrow. This lotion is primarily used for the treatment of scabies, a common parasitic skin infestation caused by the mite Sarcoptes scabiei.

Uses

Deburrow is prescribed for the treatment of scabies, which is characterized by intense itching, redness, and the presence of small, raised bumps on the skin. Scabies is highly contagious and can spread through close personal contact or by sharing contaminated clothing or bedding. Deburrow effectively kills the scabies mites and helps alleviate the symptoms associated with this condition.

Dosage and Administration

To use Deburrow, follow these general dosage instructions and methods of administration:

• Shake the bottle well before use.
• Apply a thin layer of the lotion to clean, dry skin from the neck down, including the soles of the feet.
• Massage the lotion gently into the skin until it is fully absorbed.
• Leave the lotion on for the prescribed duration, usually 8 to 14 hours, as directed by your healthcare provider.
• After the prescribed time has elapsed, wash the lotion off thoroughly with warm water and soap.

Carefully read and follow the instructions provided with the medication. If you have any questions or concerns about the dosage or administration, consult your healthcare provider.

Mechanism of Action

Permethrin, the active ingredient in Deburrow, works by disrupting the nervous system of the scabies mites. It acts on the mites’ nerve cell membranes, leading to paralysis and ultimately their death. By targeting the mites directly, Permethrin effectively eliminates the infestation and provides relief from the symptoms of scabies.

Side Effects

Common side effects may include:

• Mild skin irritation, such as itching, redness, or a temporary burning sensation at the application site.

These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as severe skin irritation or an allergic reaction (e.g., rash, swelling, difficulty breathing), discontinue use and seek immediate medical attention.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products, as they may interact with Deburrow. Some common and serious drug interactions to be aware of include:

• No significant drug interactions have been reported with Deburrow. However, it is always advisable to consult your healthcare provider or pharmacist before using any new medication to ensure there are no potential interactions.

Precautions

Before using Deburrow, take note of the following precautions:

• Contraindications: Deburrow should not be used by individuals who are hypersensitive or allergic to Permethrin or any other ingredients in the lotion.
• Pregnancy and breastfeeding: Consult your healthcare provider before using Deburrow if you are pregnant, planning to become pregnant, or breastfeeding.
• Children: Deburrow may be used in children under the guidance of a healthcare provider.
• Application to the face: Deburrow should not be applied to the face, as it may cause irritation or other adverse effects.

Be sure to discuss your medical history and any current health conditions with your healthcare provider before using Deburrow.

Storage

Deburrow should be stored at room temperature, away from excessive heat and moisture. Keep the bottle tightly closed when not in use. Do not freeze the lotion. Store the medication out of reach of children and pets.

Patient Tips

Here are some additional tips to help you make the most of your treatment with Deburrow:

• Wash all clothing, bedding, and towels that may have come into contact with the infested person’s skin or clothing.
• Vacuum carpets, upholstery, and any other areas that may have been contaminated.
• Avoid close personal contact with others until the infestation has been successfully treated.
• Follow up with your healthcare provider as directed to ensure the infestation has been fully eradicated.
• If symptoms persist or worsen after treatment, consult your healthcare provider for further evaluation.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Permethrin 5% w/w Cream (Health Professionals SmPC) Available at:
• Permethrin topical (Drugs.com) [Accessed 26 Jun. 2024] (online) Available at:
• bl permethrin liquid (RX/OTC) [Accessed 23 Jun. 2024] (online) Available at:
• Permethrin Topical (MedlinePlus) [Accessed 4 Jun. 2024] (online) Available at:
• Rosumeck S, Nast A, Dressler C. Ivermectin and permethrin for treating scabies. Cochrane Database Syst Rev. 2018 Apr 2;4(4):CD012994. doi: 10.1002/14651858.CD012994. [Accessed 13 Jun. 2024] Available at: