Dinrest 150mg Tablet SR

Introduction

Dinrest is a prescription medication that contains the active ingredient Epalrestat. It is available in tablet form and is commonly known by its brand name, Dinrest. This medication is primarily used to treat diabetic neuropathy, a condition that affects the nerves in individuals with diabetes.

Uses

Dinrest is prescribed to individuals who have been diagnosed with diabetic neuropathy. This condition can cause symptoms such as pain, numbness, and tingling in the hands and feet. By taking Dinrest, patients may experience relief from these symptoms and an improvement in their quality of life.

Dosage and Administration

The dosage of Dinrest may vary depending on the severity of the condition and the individual’s response to treatment. However, the general recommended dosage is one tablet taken once daily. Follow the instructions provided by your healthcare professional and not exceed the recommended dosage.

Dinrest should be swallowed whole with a glass of water. It is an extended-release tablet, which means it releases the medication slowly over time for a more consistent effect. Do not crush, chew, or break the tablet, as this may affect its release mechanism.

Mechanism of Action

The active ingredient in Dinrest, Epalrestat, works by inhibiting an enzyme called aldose reductase. This enzyme plays a role in the metabolism of glucose in nerve cells. By inhibiting aldose reductase, Epalrestat helps to prevent the accumulation of harmful byproducts that can damage nerves in individuals with diabetes. This mechanism of action helps to alleviate the symptoms of diabetic neuropathy.

Side Effects

Common side effects may include nausea, vomiting, stomach upset, and diarrhea. These side effects are generally mild and tend to resolve on their own without any specific treatment.

However, in rare cases, more serious side effects may occur. If you experience any of the following, seek medical attention immediately: severe allergic reactions (such as rash, itching, swelling), difficulty breathing, chest pain, or signs of liver problems (such as yellowing of the skin or eyes, dark urine, persistent nausea, or abdominal pain).

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription and over-the-counter medications, as well as any herbal supplements. Certain medications may interact with Dinrest, potentially affecting its effectiveness or increasing the risk of side effects.

Some common drug interactions with Dinrest include certain anticoagulant medications, such as warfarin, and certain anti-diabetic medications, such as sulfonylureas. Discuss all potential drug interactions with your healthcare professional before starting Dinrest.

Precautions

Before taking Dinrest, inform your healthcare professional about any allergies you may have, including allergies to medications. Additionally, let your healthcare professional know about any other medical conditions you may have, especially liver or kidney problems.

Dinrest may not be suitable for individuals who are pregnant, planning to become pregnant, or breastfeeding. Discuss the potential risks and benefits of taking this medication with your healthcare professional if you fall into any of these categories.

Storage

Dinrest should be stored at room temperature, away from moisture and heat. Keep it in its original packaging and out of the reach of children. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Dinrest exactly as prescribed by your healthcare professional. Do not alter the dosage or stop taking the medication without consulting your doctor.
• It may take some time for the medication to take effect. Be patient and continue taking it as prescribed.
• If you experience any bothersome side effects, contact your healthcare professional for guidance.
• Follow a healthy lifestyle, including regular exercise, a balanced diet, and blood sugar control, to optimize the effectiveness of Dinrest.
• Attend regular check-ups with your healthcare professional to monitor your progress and discuss any concerns you may have.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

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• Hotta N. [Epalrestat]. Nihon Rinsho. 1997 Nov;55 Suppl:204-11. [Accessed 24 Jun. 2024] Available at:
• Sato K, Tatsunami R, Wakame K. Epalrestat suppresses inflammatory response in lipopolysaccharide-stimulated RAW264.7 cells. Allergol Immunopathol (Madr). 2021 Sep 1;49(5):1-8. doi: 10.15586/aei.v49i5.102. eCollection 2021. [Accessed 17 Jun. 2024] Available at:
• Ramirez MA, Borja NL. Epalrestat: an aldose reductase inhibitor for the treatment of diabetic neuropathy. Pharmacotherapy. 2008 May;28(5):646-55. doi: 10.1592/phco.28.5.646. [Accessed 27 Jun. 2024] Available at: