Introduction
Diosartan is a prescription medication that contains Valsartan as its active ingredient. Valsartan is commonly marketed under the brand name Diosartan. It belongs to a class of medications known as angiotensin II receptor blockers (ARBs) and is primarily used to treat high blood pressure (hypertension).
Uses
Diosartan is prescribed to manage and control high blood pressure. It is often recommended as a first-line treatment for hypertension. By blocking the action of a hormone called angiotensin II, Valsartan helps relax and widen the blood vessels, allowing for smoother blood flow and reducing blood pressure levels.
Dosage and Administration
The dosage of Diosartan will vary depending on individual factors such as the severity of hypertension and other medical conditions. Follow the dosage instructions provided by your healthcare professional. Typically, the initial recommended dose for most adults is 80 to 160 mg once daily. Your doctor may adjust the dosage based on your response to the medication. The tablets should be swallowed whole with water and can be taken with or without food.
Mechanism of Action
Diosartan works by blocking the binding of angiotensin II to its receptors. Angiotensin II is a hormone that causes blood vessels to constrict, leading to increased blood pressure. By inhibiting the action of angiotensin II, Valsartan helps relax and widen the blood vessels, thereby reducing blood pressure. This mechanism of action helps prevent complications associated with high blood pressure, such as heart attacks, strokes, and kidney problems.
Side Effects
Common side effects may include dizziness, headache, fatigue, stomach upset, and cough. These side effects are usually mild and temporary.
However, be aware of potentially serious side effects that may require immediate medical attention. These can include symptoms such as:
- Severe dizziness or lightheadedness
- Rapid or irregular heartbeat
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe stomach pain or persistent nausea/vomiting
If you experience any of these serious side effects, seek medical attention right away.
Drug Interactions
Diosartan may interact with other medications, which can affect its effectiveness or increase the risk of side effects. Inform your healthcare professional about all the medications, supplements, and herbal products you are currently taking. Some common drug interactions with Valsartan include:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or naproxen
- Diuretics (water pills)
- Potassium supplements or potassium-sparing diuretics
- Lithium
- Other medications that lower blood pressure
Always consult with your healthcare professional before starting or stopping any medication while taking Diosartan.
Precautions
Before taking Diosartan, inform your healthcare professional about any existing medical conditions, allergies, or medications you are currently taking. Certain precautions should be taken into consideration, including:
- Pregnancy and breastfeeding: Diosartan should not be used during pregnancy or while breastfeeding, as it may harm the developing fetus or newborn.
- Kidney or liver problems: Valsartan may be used with caution in patients with kidney or liver problems. Regular monitoring may be required.
- Heart conditions: Inform your healthcare professional if you have any pre-existing heart conditions, as Diosartan may affect heart function.
Storage
Diosartan should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication after the expiration date printed on the packaging.
Patient Tips
- Take Diosartan exactly as prescribed by your healthcare professional. Do not adjust the dosage without consulting your doctor.
- It may take several weeks for the full benefits of the medication to be felt. Continue taking the medication regularly, even if you feel well.
- Follow a healthy lifestyle that includes a balanced diet, regular exercise, and stress management to complement the effects of Diosartan in managing your blood pressure.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
- If you have any questions or concerns about Diosartan, speak to your healthcare professional for further guidance. They are the best source of information tailored to your specific needs.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Valsartan: medicine to treat high blood pressure and heart failure (NHS UK) [Accessed 30 Jun. 2024] (online) Available at:
- Amlodipine / Valsartan 10 mg / 160 mg film-coated tablets (Health Professionals SmPC) Available at:
- Valsartan (Drugs.com) [Accessed 1 Jun. 2024] (online) Available at:
- amlodipine-valsartan (RX) [Accessed 7 Jun. 2024] (online) Available at:
- Valsartan and Sacubitril (MedlinePlus) [Accessed 10 Jun. 2024] (online) Available at:
- Docherty KF, Vaduganathan M, Solomon SD, McMurray JJV. Sacubitril/Valsartan: Neprilysin Inhibition 5 Years After PARADIGM-HF. JACC Heart Fail. 2020 Oct;8(10):800-810. doi: 10.1016/j.jchf.2020.06.020. [Accessed 1 Jun. 2024] Available at:
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