Divalpret 250mg Tablet ER

Introduction

Divalpret is a prescription medication that contains the active ingredient Sodium Valproate. It is available under the brand name Divalpret. Sodium Valproate is classified as an antiepileptic drug and is primarily used in the treatment of epilepsy and bipolar disorder.

Uses

Divalpret is prescribed for the following conditions:

• Epilepsy: Divalpret is effective in controlling seizures and preventing their recurrence in patients with epilepsy.
• Bipolar Disorder: It is also used as a mood stabilizer in the treatment of bipolar disorder. It helps to prevent or reduce the intensity of manic and depressive episodes.

Dosage and Administration

The dosage of Divalpret may vary depending on the patient’s age, weight, and medical condition. Follow the dosage instructions provided by your healthcare professional. The tablets are usually taken orally, with or without food. They should be swallowed whole and not crushed or chewed.

Mechanism of Action

Sodium Valproate, the active ingredient in Divalpret, works by increasing the levels of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain. GABA helps to reduce the excessive electrical activity that can cause seizures or mood disturbances in epilepsy and bipolar disorder.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Dizziness
• Drowsiness
• Tremor
• Weight gain

These side effects are usually mild and may go away on their own. However, if any of these side effects persist or worsen, consult your healthcare professional.

Serious side effects are rare but can occur. If you experience any of the following serious side effects, seek immediate medical attention:

• Signs of an allergic reaction (e.g., rash, itching, swelling)
• Unusual bleeding or bruising
• Yellowing of the skin or eyes (jaundice)
• Severe stomach pain
• Suicidal thoughts or behavior

Drug Interactions

inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal products. Some medications may interact with Divalpret and alter its effectiveness or increase the risk of side effects. Common drug interactions may include:

• Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs)
• Anticoagulants (blood thinners)
• Antidepressants
• Antipsychotic medications
• Other antiepileptic drugs

Inform your healthcare professional about all your current medications to ensure safe and effective use of Divalpret.

Precautions

Before taking Divalpret, consider the following precautions:

• Contraindications: Divalpret should not be used in patients with a known hypersensitivity to Sodium Valproate or any of the other ingredients in the medication. It is also contraindicated in patients with liver disease or a history of pancreatitis.
• Interactions: Inform your healthcare professional about any other medications or substances you are taking, as they may interact with Divalpret. This includes herbal supplements and over-the-counter medications.
• Pregnancy and Breastfeeding: Divalpret may cause harm to the developing fetus. Discuss the risks and benefits with your healthcare professional if you are pregnant or planning to become pregnant. It is also excreted in breast milk, so breastfeeding should be avoided while taking Divalpret.

Storage

Divalpret should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if you notice any visible signs of deterioration.

Patient Tips

• Take Divalpret exactly as prescribed by your healthcare professional.
• Do not stop or change the dosage of the medication without consulting your healthcare professional.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• If you have any concerns or questions about the medication or its side effects, consult your healthcare professional.
• attend regular check-ups with your healthcare professional to monitor your response to the medication and adjust the dosage if needed.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Sodium valproate: medicine to treat epilepsy and bipolar disorder (NHS UK) [Accessed 20 Jun. 2024] (online) Available at:
• Dyzantil 200mg prolonged-release tablets (Health Professionals SmPC) Available at:
• Depakote Capsules Dosage Guide (Drugs.com) [Accessed 15 Jun. 2024] (online) Available at:
• Valproic Acid (MedlinePlus) [Accessed 27 Jun. 2024] (online) Available at:
• Kupferberg HJ. Sodium valproate. Adv Neurol. 1980;27:643-54. [Accessed 30 Jun. 2024] Available at: