Domi 10mg Tablet

Introduction

Domi is a medication that contains the active ingredient Domperidone. It is commonly prescribed under the brand name Domi. This medication is primarily used to relieve symptoms such as nausea and vomiting, as well as to improve digestion.

Uses

Domi is prescribed for a variety of conditions, including:

• Nausea and vomiting: It can help alleviate these symptoms caused by various factors such as gastrointestinal disorders, certain medications, or post-operative recovery.
• Gastroparesis: It may be prescribed to improve gastric motility and reduce symptoms like bloating, fullness, and discomfort caused by delayed stomach emptying.
• Reflux esophagitis: It may be used to manage symptoms like heartburn, regurgitation, and difficulty swallowing associated with this condition.

Dosage and Administration

The dosage of Domi may vary depending on the specific condition being treated and the individual patient. Follow the instructions provided by your healthcare professional. In general, the recommended dosage for adults is usually 10-20 milligrams taken three to four times a day, before meals and at bedtime. The tablets should be swallowed whole with a glass of water and should not be chewed or crushed.

Mechanism of Action

Domi contains Domperidone, which belongs to a class of medications called dopamine antagonists. It works by blocking the action of dopamine in certain parts of the brain, which helps to increase the movement or contractions of the stomach and intestines. This promotes the passage of food through the digestive system and reduces symptoms such as nausea, vomiting, and bloating.

Side Effects

Domi may cause some side effects, although not everyone experiences them. Common side effects may include:

• Headache
• Dizziness
• Dry mouth
• Abdominal cramps
• Diarrhea

In rare cases, Domi may cause more serious side effects such as:

• Irregular or fast heartbeat
• Severe allergic reactions (rash, itching, swelling)
• Difficulty breathing

If you experience any of these serious side effects or any other unusual symptoms, seek medical attention immediately.

Drug Interactions

Domi may interact with other medications, including:

• Ketoconazole or other antifungal medications
• Antibiotics such as erythromycin or clarithromycin
• Medications used to treat HIV/AIDS, such as ritonavir
• Medications used to treat depression or anxiety, such as fluoxetine or paroxetine

inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.

Precautions

Before taking Domi, consider the following precautions:

• Hypersensitivity: If you have a known allergy or hypersensitivity to Domperidone or any other ingredients in the medication, you should not take Domi.
• Heart conditions: Domi may cause changes in heart rhythm, so it should be used with caution in patients with existing heart conditions or a history of abnormal heart rhythms.
• Liver or kidney problems: The dosage of Domi may need to be adjusted in patients with liver or kidney impairment.
• Pregnancy and breastfeeding: Domi should be used with caution during pregnancy and breastfeeding. Discuss the potential risks and benefits with your healthcare professional.

Storage

Domi should be stored in a cool, dry place away from direct sunlight. Keep it out of reach of children and pets. Do not use the medication after the expiration date printed on the packaging.

Patient Tips

Here are some additional tips for patients using Domi:

• Take the medication as directed by your healthcare professional. Do not exceed the recommended dosage.
• If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Avoid consuming alcohol while taking Domi, as it may increase the risk of side effects.
• If you experience any unusual or persistent symptoms while taking Domi, consult your healthcare professional for further evaluation.
• Follow a healthy diet and lifestyle to support the effectiveness of the medication in managing your symptoms.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Domperidone: anti-sickness medicine for nausea and vomiting (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Domperidone 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Domperidone (Drugs.com) [Accessed 4 Jun. 2024] (online) Available at:
• Definitions of Digestive Terms (International Foundation for Gastrointestinal Disorders) [Accessed 3 Jun. 2024] (online) Available at:
• Puoti MG, Assa A, Benninga M, Broekaert IJ, Carpi FJM, Deganello Saccomani M, Dolinsek J, Homan M, Mas E, Miele E, Tzivinikos C, Thomson M, Borrelli O. Drugs in Focus: Domperidone. J Pediatr Gastroenterol Nutr. 2023 Aug 1;77(2):e13-e22. doi: 10.1097/MPG.0000000000003822. Epub 2023 May 9. [Accessed 7 Jun. 2024] Available at: