Introduction
Dosof R is a prescription medication that contains two active ingredients: Diclofenac and Rabeprazole. Diclofenac belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs), while Rabeprazole is a proton pump inhibitor (PPI). This combination medication is commonly prescribed to provide relief from pain and reduce inflammation, as well as to prevent and treat gastric ulcers associated with the use of NSAIDs.
Uses
Dosof R is primarily used to manage pain and inflammation caused by conditions such as arthritis, menstrual cramps, and injuries. It is also prescribed to prevent and treat gastric ulcers that may occur as a result of long-term NSAID use. By reducing the production of stomach acid, Rabeprazole helps to protect the stomach lining and prevent the formation of ulcers.
Dosage and Administration
The dosage of Dosof R will vary depending on the specific condition being treated and the individual patient. Follow your healthcare provider’s instructions regarding the dosage and duration of treatment. Typically, the recommended dose for adults is one tablet taken orally, with or without food, once or twice daily. Swallow the tablet whole and not crush or chew it.
Mechanism of Action
Diclofenac, one of the active ingredients in Dosof R, works by inhibiting the production of certain chemicals in the body that cause pain and inflammation. It does this by blocking the action of an enzyme called cyclooxygenase (COX), which is involved in the production of these chemicals. Rabeprazole, on the other hand, works by reducing the production of stomach acid, thereby protecting the stomach lining and preventing the formation of ulcers.
Side Effects
Common side effects may include nausea, stomach pain, indigestion, diarrhea, and headache. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as severe stomach pain, black or tarry stools, or signs of an allergic reaction (e.g., rash, itching, swelling), seek medical attention immediately.
Drug Interactions
Dosof R may interact with other medications, including blood thinners, certain antidepressants, and diuretics. Inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid any potential drug interactions. Your healthcare provider will be able to determine whether Dosof R is safe for you to use in combination with other medications.
Precautions
Before taking Dosof R, inform your healthcare provider about any existing medical conditions, especially if you have a history of stomach ulcers, kidney disease, liver disease, or heart disease. This medication should be used with caution in patients with these conditions. Avoid alcohol consumption while taking Dosof R, as it may increase the risk of stomach bleeding.
Storage
Dosof R should be stored at room temperature, away from moisture and heat. Keep the medication out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.
Patient Tips
- Follow your healthcare provider’s instructions regarding the dosage and duration of treatment.
- Take Dosof R with or without food, as directed.
- Swallow the tablet whole and do not crush or chew it.
- If you experience any severe or persistent side effects, seek medical attention immediately.
- Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions.
- Avoid alcohol consumption while taking Dosof R.
- Store the medication at room temperature, away from moisture and heat.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Diclofenac: a non-steroidal anti-inflammatory drug (NSAID) for pain and swelling (NHS UK) [Accessed 0 Jun. 2024] (online) Available at:
- Diclofenac 2.32% gel (Health Professionals SmPC) Available at:
- Diclofenac (Drugs.com) [Accessed 28 Jun. 2024] (online) Available at:
- aleve (diclofenac) 1 % topical gel non-steroidal anti-inflammatory agents (nsaid) (OTC) [Accessed 20 Jun. 2024] (online) Available at:
- Diclofenac Topical (arthritis pain) [Accessed 5 Jun. 2024] (online) Available at:
- Hamed R, Mahmoud NN, Alnadi SH, Alkilani AZ, Hussein G. Diclofenac diethylamine nanosystems-loaded bigels for topical delivery: development, rheological characterization, and release studies. Drug Dev Ind Pharm. 2020 Oct;46(10):1705-1715. doi: 10.1080/03639045.2020.1820038. Epub 2020 Sep 18. [Accessed 23 Jun. 2024] Available at:
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