Doxirol Softgel Capsule

Introduction

Doxirol Softgel is a prescription medication that contains the active ingredient Calcitriol. It is available in capsule form and is commonly prescribed by healthcare professionals.

Uses

Doxirol Softgel is primarily used to treat and manage conditions related to calcium and vitamin D metabolism in the body. It is often prescribed for patients with chronic kidney disease or those undergoing dialysis, as these conditions can lead to imbalances in calcium and vitamin D levels.

Dosage and Administration

follow your healthcare professional’s instructions when taking Doxirol Softgel. The dosage may vary depending on your specific condition and medical history. Typically, the recommended starting dose for adults is 0.25 micrograms (mcg) to 0.5 mcg once daily. However, your healthcare professional may adjust the dosage based on your individual needs.

The capsule should be swallowed whole with water, preferably with meals to enhance absorption. Do not crush, chew, or break the capsule unless instructed by your healthcare professional.

Mechanism of Action

Calcitriol, the active ingredient in Doxirol Softgel, is a form of vitamin D that helps regulate calcium and phosphate levels in the body. It promotes the absorption of calcium from the intestine and helps maintain proper calcium and phosphate balance in the bones.

Side Effects

Common side effects may include nausea, vomiting, constipation, increased thirst, and frequent urination. These side effects are usually mild and temporary. However, if you experience any persistent or severe side effects, consult your healthcare professional.

In rare cases, Doxirol Softgel may cause more serious side effects such as high blood calcium levels (hypercalcemia), which may manifest as symptoms like increased urination, excessive thirst, constipation, confusion, or weakness. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription medications, over-the-counter drugs, and herbal supplements. Some medications may interact with Doxirol Softgel and affect its effectiveness or increase the risk of side effects.

Common drug interactions may include thiazide diuretics, digoxin, and certain antacids. These medications may alter the levels of calcium in the body and can potentially interfere with the action of Doxirol Softgel. Your healthcare professional will closely monitor your medication regimen and adjust the dosages accordingly to minimize any potential interactions.

Precautions

Before starting Doxirol Softgel, inform your healthcare professional if you have any known allergies or medical conditions. This medication may not be suitable for everyone, especially those with a history of hypercalcemia, vitamin D toxicity, or kidney stones.

Doxirol Softgel should be used with caution in patients with certain medical conditions, such as liver or kidney disease, as dosage adjustments may be necessary.

Additionally, some medications or substances may interact with Doxirol Softgel, including thiazide diuretics, digoxin, and certain antacids. Discuss all your current medications with your healthcare professional to prevent any potential interactions.

Storage

Doxirol Softgel should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take the medication exactly as prescribed by your healthcare professional.
• It is advisable to take Doxirol Softgel with meals, as this can enhance its absorption.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not exceed the prescribed dosage unless instructed by your healthcare professional.
• Inform your healthcare professional about any persistent or severe side effects you experience.
• Attend all scheduled appointments with your healthcare professional for regular monitoring of your calcium and vitamin D levels.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Common questions about colecalciferol (NHS UK) [Accessed 4 Jun. 2024] (online) Available at:
• Rocaltrol 0.25 and 0.5 microgram Capsules (Health Professionals SmPC) Available at:
• Calcitriol (Drugs.com) [Accessed 12 Jun. 2024] (online) Available at:
• calcitriol (RX) [Accessed 20 Jun. 2024] (online) Available at:
• Calcitriol Topical (MedlinePlus) [Accessed 27 Jun. 2024] (online) Available at:
• Donati S, Palmini G, Aurilia C, Falsetti I, Miglietta F, Iantomasi T, Brandi ML. Rapid Nontranscriptional Effects of Calcifediol and Calcitriol. Nutrients. 2022 Mar 18;14(6):1291. doi: 10.3390/nu14061291. [Accessed 20 Jun. 2024] Available at: