Doxokast 400mg/10mg Tablet

Introduction

Doxokast is a prescription medication that combines the active ingredients Doxofylline and Montelukast. Doxofylline is a bronchodilator that helps to relax the muscles in the airways, making it easier to breathe. Montelukast is a leukotriene receptor antagonist that works by blocking the action of certain substances in the body that cause inflammation and narrowing of the airways. Doxokast is primarily used for the management of asthma and chronic obstructive pulmonary disease (COPD).

Uses

Doxokast is prescribed to treat and prevent symptoms of asthma and COPD. It helps to relieve symptoms such as wheezing, shortness of breath, coughing, and chest tightness. This medication is suitable for both adults and children above the age of 12 who have been diagnosed with asthma or COPD.

Dosage and Administration

The dosage of Doxokast will vary depending on the patient’s age, medical condition, and response to treatment. Follow the instructions provided by your healthcare professional or as indicated on the prescription label. Generally, the recommended dose for adults is one tablet taken orally twice a day, with or without food. For children aged 12 to 17, the dosage is one tablet taken once daily. It is important not to exceed the prescribed dose without consulting your doctor.

Mechanism of Action

Doxofylline in Doxokast works by relaxing the smooth muscles in the airways, which helps to improve airflow to the lungs. This allows for easier breathing and reduces symptoms such as wheezing and shortness of breath. Montelukast, on the other hand, works by blocking certain substances called leukotrienes, which are involved in the inflammatory process in the airways. By blocking the action of leukotrienes, Montelukast helps to reduce inflammation and prevent the narrowing of the airways.

Side Effects

Common side effects may include headache, dizziness, nausea, vomiting, stomach upset, and diarrhea. These side effects are usually mild and temporary. However, if any of these side effects persist or worsen, inform your doctor.

Serious side effects of Doxokast are rare but can occur. These may include allergic reactions such as rash, itching, swelling of the face, lips, or tongue, difficulty breathing, or severe dizziness. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Doxokast may interact with certain medications, including theophylline, warfarin, phenytoin, and rifampin. These interactions can affect the effectiveness of the medication or increase the risk of side effects. Your doctor will carefully consider these potential interactions when prescribing Doxokast and may adjust the dosage or recommend alternative medications if necessary.

Precautions

Before taking Doxokast, inform your doctor about any known allergies or medical conditions you may have. This medication may not be suitable for individuals with certain medical conditions, such as a history of heart problems, liver or kidney disease, or seizures. Disclose if you are pregnant, planning to become pregnant, or breastfeeding, as Doxokast may not be recommended in these situations.

Doxokast may interact with certain medications, including other bronchodilators, anticoagulants, anticonvulsants, and rifampin. Additionally, avoid consuming large amounts of caffeine or alcohol while taking this medication, as they may increase the risk of side effects.

Storage

Doxokast should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use this medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Doxokast exactly as prescribed by your doctor. Do not exceed the recommended dose.
• If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• continue taking Doxokast even if you feel well, as it is a long-term treatment for asthma and COPD.
• If you experience any new or worsening symptoms while taking Doxokast, such as increased shortness of breath or chest pain, contact your doctor immediately.
• Avoid exposure to triggers that may worsen your asthma or COPD symptoms, such as smoke, allergens, and respiratory infections.
• Regularly monitor your lung function using a peak flow meter or spirometry as directed by your healthcare professional.
• Attend regular follow-up appointments with your doctor to monitor your response to treatment and make any necessary adjustments.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Montelukast: a medicine to prevent asthma symptoms (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Montelukast 10 mg film-coated tablets (Health Professionals SmPC) Available at:
• Doxofylline (International database) (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• montelukast (singulair) (RX) [Accessed 25 Jun. 2024] (online) Available at:
• Montelukast (MedlinePlus) [Accessed 22 Jun. 2024] (online) Available at:
• Matera MG, Page C, Cazzola M. Doxofylline is not just another theophylline! Int J Chron Obstruct Pulmon Dis. 2017 Dec 5;12:3487-3493. doi: 10.2147/COPD.S150887. eCollection 2017. [Accessed 8 Jun. 2024] Available at: