Dubinac-SR Tablet

Introduction

Dubinac-SR is a prescription medication that contains two active ingredients: Aceclofenac and Pregabalin. It is commonly used to provide relief from pain and inflammation associated with various conditions. This medication is available under the brand name Dubinac-SR.

Uses

Dubinac-SR is primarily prescribed for the treatment of pain and inflammation caused by conditions such as arthritis, osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It may also be used to alleviate neuropathic pain, which is caused by nerve damage.

Dosage and Administration

The dosage of Dubinac-SR will vary depending on the specific condition being treated and the individual patient. Follow the instructions provided by your healthcare provider or the information on the prescription label. Generally, the usual recommended dose is one tablet taken orally, with or without food, once or twice a day.

Mechanism of Action

Aceclofenac, one of the active ingredients in Dubinac-SR, belongs to a class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation.

Pregabalin, the other active ingredient, is an antiepileptic drug that is also used to treat certain types of nerve pain. It works by reducing the abnormal electrical activity in the brain that can cause seizures and by modulating the release of certain neurotransmitters involved in pain signaling.

Side Effects

Common side effects may include nausea, dizziness, headache, stomach pain, and diarrhea. These side effects are usually mild and temporary.

However, some individuals may experience more serious side effects, such as signs of an allergic reaction (e.g., rash, itching, swelling, severe dizziness), black or bloody stools, chest pain, difficulty breathing, or signs of liver or kidney problems. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Dubinac-SR may interact with certain other medications, including other nonsteroidal anti-inflammatory drugs (NSAIDs), blood thinners, certain antidepressants, and certain antiepileptic drugs. These drug interactions can potentially increase the risk of side effects or affect the efficacy of either medication.

Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to ensure that there are no potential drug interactions.

Precautions

Before taking Dubinac-SR, inform your healthcare provider about any existing medical conditions you have, especially if you have a history of stomach ulcers, bleeding disorders, liver or kidney disease, heart problems, or if you are pregnant or breastfeeding.

This medication should be used with caution in elderly patients, as they may be more susceptible to certain side effects. Avoid alcohol consumption while taking Dubinac-SR, as it can increase the risk of stomach bleeding and other side effects.

Storage

Dubinac-SR should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication if it has exceeded its expiration date.

Patient Tips

• Take Dubinac-SR exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or take it for longer than instructed.
• If you experience any unusual or bothersome side effects while taking this medication, contact your healthcare provider.
• Avoid activities that require mental alertness, such as driving or operating machinery, if you experience dizziness or drowsiness while taking Dubinac-SR.
• attend regular check-ups with your healthcare provider to monitor your response to the medication and to address any concerns or questions you may have.
• If you have any doubts or questions regarding the use of Dubinac-SR, consult your healthcare provider or pharmacist for further information.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Pregabalin: medicine to treat epilepsy and anxiety (NHS UK) [Accessed 18 Jun. 2024] (online) Available at:
• Aceclofenac 100 mg Film-coated Tablets (Health Professionals SmPC) Available at:
• ACECLOFENAC 100MG TABLETS (Drugs.com) [Accessed 11 Jun. 2024] (online) Available at:
• pregabalin (lyrica) (RX) [Accessed 18 Jun. 2024] (online) Available at:
• Pregabalin (MedlinePlus) [Accessed 18 Jun. 2024] (online) Available at:
• Negi S, Tandel N, Sharma P, Kumar R, Tyagi RK. Aceclofenac and methotrexate combination therapy could influence Th1/Th17 axis to modulate rheumatoid-arthritis-induced inflammation. Drug Discov Today. 2023 Aug;28(8):103671. doi: 10.1016/j.drudis.2023.103671. Epub 2023 Jun 16. [Accessed 25 Jun. 2024] Available at: