Dulomit P 75mg/20mg Tablet

Introduction

Dulomit P is a prescription medication that combines two active ingredients: Pregabalin and Duloxetine. It is available under the brand name Dulomit P. This medication is primarily used to manage certain neurological and psychiatric conditions.

Uses

Dulomit P is commonly prescribed for the following conditions:

• Neuropathic pain: It can be used to alleviate pain caused by damaged nerves, often seen in conditions such as diabetic neuropathy or post-herpetic neuralgia.
• Fibromyalgia: Dulomit P can help reduce the pain and improve the quality of life in individuals with fibromyalgia, a chronic condition characterized by musculoskeletal pain and tenderness.
• Generalized Anxiety Disorder (GAD): This medication is also used to treat GAD, a mental health disorder characterized by excessive and persistent worrying.
• Major Depressive Disorder (MDD): Dulomit P is sometimes prescribed to manage the symptoms of depression, helping to improve mood and overall well-being.

Dosage and Administration

follow your healthcare provider’s instructions regarding the dosage and administration of Dulomit P. The recommended dosage may vary depending on the specific condition being treated and individual patient factors. Typically, the initial dose is low and gradually increased to achieve the desired therapeutic effect.

Dulomit P is usually taken orally, with or without food. Swallow the tablet whole with a glass of water, and do not crush or chew it. If you have difficulty swallowing, consult your healthcare provider for alternative options.

Mechanism of Action

Dulomit P contains two active ingredients with distinct mechanisms of action:

• Pregabalin: It is thought to work by reducing the release of certain neurotransmitters in the brain, thereby decreasing the abnormal electrical activity that contributes to pain and seizures.
• Duloxetine: This ingredient belongs to a class of medications called serotonin-norepinephrine reuptake inhibitors (SNRIs). It helps restore the balance of certain chemicals in the brain, such as serotonin and norepinephrine, which play a role in mood regulation and pain perception.

The combination of these two ingredients in Dulomit P provides a synergistic effect in managing the symptoms associated with neuropathic pain, fibromyalgia, GAD, and MDD.

Side Effects

Common side effects may include dizziness, drowsiness, dry mouth, constipation, and nausea. These side effects are usually mild and temporary.

However, some individuals may experience more serious side effects, such as suicidal thoughts, unusual bleeding or bruising, or allergic reactions (rash, itching, swelling). If you experience any severe or persistent side effects, seek medical attention immediately.

Drug Interactions

Dulomit P may interact with other medications, including but not limited to:

• Monoamine oxidase inhibitors (MAOIs)
• Selective serotonin reuptake inhibitors (SSRIs)
• Other serotonin-norepinephrine reuptake inhibitors (SNRIs)
• Warfarin or other anticoagulants
• Nonsteroidal anti-inflammatory drugs (NSAIDs)
• Alcohol or other central nervous system depressants

inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid potential drug interactions.

Precautions

Before taking Dulomit P, consider the following precautions:

• Allergy: If you are allergic to Pregabalin, Duloxetine, or any other ingredients in Dulomit P, inform your healthcare provider.
• Pregnancy and breastfeeding: Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before starting this medication.
• Medical conditions: Inform your healthcare provider about any medical conditions you have, including liver or kidney problems, epilepsy, or a history of drug abuse.

Additionally, Dulomit P may increase the risk of suicidal thoughts, especially in individuals under the age of 25. Close monitoring by a healthcare provider is essential, especially during the initial weeks of treatment or dosage adjustments.

Storage

Store Dulomit P at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use the medication beyond its expiration date, and properly dispose of any unused or expired medication in accordance with local regulations.

Patient Tips

• Take the medication as prescribed by your healthcare provider. Do not change the dosage or stop taking it without consulting your healthcare provider.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for the next dose, skip the missed dose and continue with the regular dosing schedule.
• Attend regular follow-up appointments with your healthcare provider to monitor your progress and discuss any concerns or side effects you may be experiencing.
• Avoid consuming alcohol while taking Dulomit P, as it may increase the risk of side effects.
• Be cautious when operating machinery or driving, as Dulomit P may cause dizziness or drowsiness.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Duloxetine: medicine to treat depression and anxiety (NHS UK) [Accessed 23 Jun. 2024] (online) Available at:
• Cymbalta 30mg hard gastro-resistant capsules (Health Professionals SmPC) Available at:
• Duloxetine (Drugs.com) [Accessed 7 Jun. 2024] (online) Available at:
• duloxetine 60 mg capsule,delayed release sprinkle (RX) [Accessed 12 Jun. 2024] (online) Available at:
• Duloxetine (MedlinePlus) [Accessed 15 Jun. 2024] (online) Available at:
• Migliorini F, Maffulli N, Eschweiler J, Baroncini A, Bell A, Colarossi G. Duloxetine for fibromyalgia syndrome: a systematic review and meta-analysis. J Orthop Surg Res. 2023 Jul 17;18(1):504. doi: 10.1186/s13018-023-03995-z. [Accessed 8 Jun. 2024] Available at: