Empime-S Injection

Introduction

Empime-S is a prescription medication that contains the active ingredients Cefepime and Sulbactam. It is available in injectable form and is primarily used to treat bacterial infections.

Uses

Empime-S is prescribed for the treatment of various bacterial infections, including respiratory tract infections, skin and soft tissue infections, urinary tract infections, and intra-abdominal infections. It is commonly used in hospitals and healthcare settings when oral antibiotics are not suitable or effective.

Dosage and Administration

The dosage of Empime-S will vary depending on the severity of the infection, the patient’s age, weight, and overall health. It is typically administered by a healthcare professional through an intravenous (IV) infusion over a specific period of time.

Follow the dosage instructions provided by your healthcare provider. Do not self-administer this medication without proper medical supervision.

Mechanism of Action

Empime-S contains two active ingredients: Cefepime and Sulbactam. Cefepime is a cephalosporin antibiotic that works by inhibiting the growth of bacteria, while Sulbactam is a beta-lactamase inhibitor that helps to enhance the activity of Cefepime against certain bacteria.

Together, these ingredients work to effectively treat bacterial infections by preventing the bacteria from multiplying and causing further harm.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, headache, and inflammation at the injection site. These side effects are usually mild and temporary.

However, some individuals may experience more serious side effects that require immediate medical attention. These may include severe allergic reactions, such as difficulty breathing, swelling of the face, lips, tongue, or throat, and rash. If you experience any of these symptoms, seek medical help right away.

Drug Interactions

Empime-S may interact with other medications, including certain antibiotics, anticoagulants, and diuretics. Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid any potential drug interactions.

Precautions

Before using Empime-S, inform your healthcare provider if you have any known allergies to Cefepime, Sulbactam, or any other cephalosporin antibiotics. Additionally, let your healthcare provider know about any medical conditions you have, especially kidney problems.

Empime-S should be used with caution in patients with a history of allergies, including penicillin allergies, as there may be a cross-reactivity. Follow your healthcare provider’s instructions and report any unusual symptoms or reactions.

Storage

Empime-S should be stored in a cool, dry place away from direct sunlight. It should be kept out of the reach of children and pets. Do not use the medication if it has passed the expiration date or if the solution appears discolored or contains particles.

Patient Tips

• complete the full course of treatment as prescribed by your healthcare provider, even if you start to feel better before the treatment is finished.
• If you miss a dose, contact your healthcare provider for further instructions.
• Drink plenty of fluids while receiving Empime-S to stay hydrated.
• Inform your healthcare provider if you develop any new symptoms or if your condition worsens during treatment.
• Follow proper hand hygiene practices and maintain cleanliness to prevent the spread of infection.
• If you have any concerns or questions about Empime-S, do not hesitate to consult your healthcare provider for clarification.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• EXBLIFEP 2 g/0.5 g powder for concentrate for solution for infusion (Health Professionals SmPC) Available at:
• Cefepime injection (Drugs.com) [Accessed 27 Jun. 2024] (online) Available at:
• cefepime hcl vial (RX) [Accessed 12 Jun. 2024] (online) Available at:
• Cefepime Injection (MedlinePlus) [Accessed 27 Jun. 2024] (online) Available at:
• Wagenlehner FM, Gasink LB, McGovern PC, Moeck G, McLeroth P, Dorr M, Dane A, Henkel T; CERTAIN-1 Study Team. Cefepime-Taniborbactam in Complicated Urinary Tract Infection. N Engl J Med. 2024 Feb 15;390(7):611-622. doi: 10.1056/NEJMoa2304748. [Accessed 7 Jun. 2024] Available at: