Endokine 300mcg Injection

Introduction

Endokine is a medication that contains the active ingredient Filgrastim. It is available under the brand name Endokine. Filgrastim is a synthetic form of a naturally occurring protein called granulocyte colony-stimulating factor (G-CSF). This medication is primarily used to stimulate the production of white blood cells in the body.

Uses

Endokine is prescribed to individuals who have undergone certain types of chemotherapy or bone marrow transplantation. It is also used in patients with severe chronic neutropenia, a condition characterized by a low level of neutrophils (a type of white blood cell). By increasing the production of white blood cells, Endokine helps to strengthen the immune system and reduce the risk of infections.

Dosage and Administration

The dosage of Endokine may vary depending on the specific condition being treated and the individual patient. It is typically administered as an injection under the skin or into a vein by a healthcare professional. The exact dosage and frequency of administration will be determined by your doctor. Follow the instructions provided by your healthcare provider and not to change the dosage without consulting them.

Mechanism of Action

Filgrastim, the active ingredient in Endokine, works by stimulating the bone marrow to produce more white blood cells, particularly neutrophils. Neutrophils are an important component of the immune system and play a crucial role in fighting off infections. By increasing the production of neutrophils, Endokine helps to restore and strengthen the immune system, reducing the risk of infections in patients undergoing certain treatments or with low neutrophil levels.

Side Effects

Common side effects may include bone pain, headache, fatigue, fever, and injection site reactions such as redness, swelling, or discomfort. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, contact your healthcare provider immediately.

In rare cases, Endokine may cause more serious side effects, such as allergic reactions, difficulty breathing, or swelling of the face, lips, tongue, or throat. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications may interact with Endokine, potentially affecting its effectiveness or increasing the risk of side effects. Your healthcare provider will consider these potential interactions when prescribing Endokine and may adjust the dosage or recommend alternative medications if necessary.

Precautions

Before starting treatment with Endokine, inform your healthcare provider about any existing medical conditions, allergies, or medications you are taking. This medication may not be suitable for individuals with certain conditions, such as a history of allergic reactions to Filgrastim or any other component of the injection. Additionally, Endokine should be used with caution in patients with sickle cell disease or those at risk of spleen rupture.

Storage

Endokine should be stored in a refrigerator between 2°C and 8°C (36°F and 46°F) and should not be frozen. Keep the medication in its original packaging until ready for use. Do not use Endokine if it has been frozen or if it has expired. If you have any questions about storage or the condition of the medication, consult your pharmacist.

Patient Tips

• follow the specific instructions provided by your healthcare provider for the administration of Endokine.
• If you have any concerns or questions about the medication, do not hesitate to reach out to your healthcare provider or pharmacist.
• Keep a record of the dates and times of your injections to ensure you are taking the medication as prescribed.
• If you miss a dose, contact your healthcare provider for instructions on what to do.
• Stay hydrated and maintain good nutrition while using Endokine to support your overall health.
• If you experience any new or worsening symptoms while using Endokine, inform your healthcare provider promptly.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Neupogen 30 MU (0.3 mg/ml) solution for injection (Health Professionals SmPC) Available at:
• Filgrastim (Drugs.com) [Accessed 0 Jun. 2024] (online) Available at:
• filgrastim (RX) [Accessed 19 Jun. 2024] (online) Available at:
• Filgrastim Injection (MedlinePlus) [Accessed 22 Jun. 2024] (online) Available at:
• Dale DC, Crawford J, Klippel Z, Reiner M, Osslund T, Fan E, Morrow PK, Allcott K, Lyman GH. A systematic literature review of the efficacy, effectiveness, and safety of filgrastim. Support Care Cancer. 2018 Jan;26(1):7-20. doi: 10.1007/s00520-017-3854-x. Epub 2017 Sep 22. [Accessed 30 Jun. 2024] Available at: