Introduction
Enpag is a prescription medication that contains the active ingredient Empagliflozin. It is commonly marketed under the brand name Enpag. This medication is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus.
Uses
Enpag is prescribed to treat type 2 diabetes mellitus. It is used in combination with a healthy diet and regular exercise to help control blood sugar levels. This medication helps to lower blood glucose by increasing the excretion of glucose through the kidneys.
Dosage and Administration
Enpag should be taken exactly as prescribed by your healthcare provider. The recommended dosage may vary depending on individual factors such as your medical condition, response to treatment, and other medications you may be taking. Follow your healthcare provider’s instructions carefully.
The tablets should be swallowed whole with a glass of water. They can be taken with or without food. If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.
Mechanism of Action
Empagliflozin, the active ingredient in Enpag, belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It works by inhibiting the SGLT2 protein in the kidneys, which is responsible for reabsorbing glucose from the urine back into the bloodstream. By blocking this protein, Empagliflozin helps to increase the excretion of glucose through the urine, thereby lowering blood sugar levels.
Side Effects
Common side effects that have been reported include urinary tract infections, genital yeast infections, increased urination, and thirst. These side effects are generally mild and may resolve on their own. However, if they persist or worsen, consult your healthcare provider.
In rare cases, Enpag may cause serious side effects such as ketoacidosis (a serious condition characterized by high levels of ketones in the blood) and kidney problems. Seek immediate medical attention if you experience symptoms such as persistent nausea, vomiting, abdominal pain, unusual fatigue, or difficulty breathing.
Drug Interactions
inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications may interact with Enpag and affect its effectiveness or increase the risk of side effects.
Common drug interactions include diuretics, such as furosemide, and medications that lower blood pressure, such as ACE inhibitors or angiotensin receptor blockers. These medications may increase the risk of low blood pressure when taken concomitantly with Enpag. Your healthcare provider will closely monitor your blood pressure and adjust your treatment if necessary.
Precautions
Before starting treatment with Enpag, inform your healthcare provider about any medical conditions you have, especially if you have a history of kidney problems or urinary tract infections. This medication may increase the risk of these conditions.
Enpag is not recommended for use in individuals with type 1 diabetes or diabetic ketoacidosis. It is also contraindicated in patients with severe renal impairment or end-stage renal disease.
Additionally, avoid excessive alcohol consumption while taking Enpag, as it may increase the risk of side effects.
Storage
Store Enpag at room temperature, away from moisture and heat. Keep it in its original packaging and out of reach of children.
Patient Tips
- Follow your healthcare provider’s instructions for taking Enpag.
- Maintain a healthy diet and engage in regular exercise to help control blood sugar levels.
- Monitor your blood sugar levels regularly as directed by your healthcare provider.
- Stay hydrated and drink plenty of water while taking this medication.
- Report any unusual or persistent side effects to your healthcare provider.
- Keep all follow-up appointments with your healthcare provider for monitoring and adjustment of your treatment if necessary.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Empagliflozin: a medicine to treat type 2 diabetes (NHS UK) [Accessed 21 Jun. 2024] (online) Available at:
- Glyxambi 10 mg/5 mg Film-coated Tablets (Health Professionals SmPC) Available at:
- Empagliflozin (Drugs.com) [Accessed 20 Jun. 2024] (online) Available at:
- empagliflozin 10 mg-linagliptin 5 mg-metformin er 1,000 mg tablet,24hr (RX) [Accessed 16 Jun. 2024] (online) Available at:
- Empagliflozin (MedlinePlus) [Accessed 5 Jun. 2024] (online) Available at:
- Cai C, Guo Z, Chang X, Li Z, Wu F, He J, Cao T, Wang K, Shi N, Zhou H, Toan S, Muid D, Tan Y. Empagliflozin attenuates cardiac microvascular ischemia/reperfusion through activating the AMPKalpha1/ULK1/FUNDC1/mitophagy pathway. Redox Biol. 2022 Jun;52:102288. doi: 10.1016/j.redox.2022.102288. Epub 2022 Mar 18. [Accessed 14 Jun. 2024] Available at:
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