Equirab 1500 Injection

Introduction

Equirab is a prescription medication that contains Equine Rabies Immunoglobulin as its active ingredient. Equine Rabies Immunoglobulin is a specialized formulation made from horse plasma that contains antibodies against the rabies virus. This medication is primarily used for post-exposure prophylaxis in individuals who have been exposed to the rabies virus.

Uses

Equirab is prescribed for the prevention of rabies infection in individuals who have been exposed to the rabies virus. It is used as part of a comprehensive treatment regimen that includes wound care, administration of rabies vaccine, and appropriate medical management.

Dosage and Administration

Equirab is administered by a healthcare professional, usually in a hospital or clinic setting. The dosage and administration of this medication may vary based on factors such as the individual’s weight, the severity of the exposure, and the specific treatment guidelines recommended by healthcare authorities. Follow the instructions provided by your healthcare provider regarding the dosage and administration of Equirab.

Mechanism of Action

Equine Rabies Immunoglobulin works by providing passive immunity against the rabies virus. When administered, the antibodies in Equirab bind to the rabies virus and help neutralize its effects, reducing the risk of developing rabies infection. This mechanism of action provides immediate protection while the individual’s own immune system produces an active immune response through vaccination.

Side Effects

Common side effects may include pain or discomfort at the injection site, mild fever, headache, and nausea. These side effects are usually temporary and resolve on their own.

Serious side effects are rare but can occur. If you experience any severe allergic reactions such as difficulty breathing, hives, or swelling of the face, lips, tongue, or throat, seek immediate medical attention.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. There are no known drug interactions with Equirab. However, it is always best to consult with your healthcare provider to ensure the safe and effective use of this medication.

Precautions

Before receiving Equirab, inform your healthcare provider if you have any known allergies to horse products or any other medications. Disclose your medical history, especially if you have a history of immune system disorders or any other serious medical conditions.

Equirab is contraindicated in individuals who have had a severe allergic reaction to horse products or any of the components of this medication. Discuss any potential risks and benefits with your healthcare provider before receiving this medication.

Storage

Equirab should be stored in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Keep it in the original packaging and protect it from light. Do not use Equirab if it has been frozen or if the expiration date has passed.

Patient Tips

• Follow the instructions provided by your healthcare provider regarding the administration of Equirab.
• Inform your healthcare provider about any medications you are currently taking before receiving this medication.
• If you experience any severe allergic reactions or side effects after receiving Equirab, seek immediate medical attention.
• Store Equirab in the refrigerator as directed and do not freeze it.
• Keep the medication out of the reach of children and pets.
• Dispose of any unused or expired medication properly, in accordance with local regulations and guidelines.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Rabies (NHS UK) [Accessed 0 Jun. 2024] (online) Available at:
• KedRAB (rabies immunoglobulin human) FDA Approval History (Drugs.com) [Accessed 1 Jun. 2024] (online) Available at:
• Encephalitis (National Institute of Neurological Disorders and Stroke) [Accessed 17 Jun. 2024] (online) Available at:
• Fan L, Zhang L, Li J, Zhu F. Advances in the progress of monoclonal antibodies for rabies. Hum Vaccin Immunother. 2022 Dec 31;18(1):2026713. doi: 10.1080/21645515.2022.2026713. Epub 2022 Feb 16. [Accessed 6 Jun. 2024] Available at: