Fenabrate 160mg Tablet

Introduction

Fenabrate is a medication that contains the active ingredient fenofibrate. It is available under the brand name Fenabrate. This medication is primarily used to help lower high levels of cholesterol and triglycerides in the blood.

Uses

Fenabrate is prescribed to patients with high cholesterol and triglyceride levels. It is often recommended as an adjunct to a healthy diet and lifestyle changes to help reduce the risk of cardiovascular diseases, such as heart attacks and strokes. This medication works by decreasing the production of cholesterol and triglycerides in the liver and increasing the breakdown of fats in the blood.

Dosage and Administration

The dosage of Fenabrate may vary depending on individual patient factors and the severity of the condition being treated. Follow the instructions provided by your healthcare professional or the information on the medication label. Typically, the recommended starting dose for adults is 145 mg once daily with food. The dosage may be adjusted by your healthcare professional based on your response to treatment and lipid profile.

It is advisable to swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet before swallowing, as it may affect the medication’s efficacy. Take this medication regularly and at the same time each day to achieve the best possible results.

Mechanism of Action

The active ingredient in Fenabrate, fenofibrate, belongs to a class of medications known as fibrates. Fenofibrate works by activating certain enzymes that help break down cholesterol and triglycerides in the liver. This leads to a decrease in the production of cholesterol and triglycerides and an increase in the breakdown of fats in the blood. By reducing the levels of these lipids, fenofibrate helps improve overall lipid profile and reduces the risk of cardiovascular diseases.

Side Effects

Common side effects may include headache, abdominal pain, nausea, and diarrhea. These side effects are usually mild and temporary. However, if they persist or become bothersome, consult your healthcare professional.

In rare cases, Fenabrate may cause more serious side effects. These can include muscle pain, weakness, or tenderness, which may be a sign of a rare but serious condition called rhabdomyolysis. If you experience any unexplained muscle pain or weakness, seek medical attention immediately. Other serious side effects may include liver problems or allergic reactions. If you notice any symptoms such as yellowing of the skin or eyes, dark urine, or difficulty breathing, seek medical help right away.

Drug Interactions

Fenabrate may interact with certain medications, which can affect its effectiveness or increase the risk of side effects. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Common medications that may interact with Fenabrate include anticoagulants (blood thinners), certain types of diabetes medications, and certain cholesterol-lowering medications. Your healthcare professional will be able to determine if any adjustments to your medication regimen are necessary.

Precautions

Before taking Fenabrate, inform your healthcare professional about any medical conditions you may have, especially if you have liver or kidney problems, gallbladder disease, or a history of pancreatitis. Additionally, inform your healthcare professional about any allergies you may have.

This medication is generally not recommended during pregnancy or breastfeeding, as its effects on the unborn baby or nursing infant are not well-established. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare professional for appropriate alternatives.

Storage

Fenabrate should be stored at room temperature, away from direct sunlight and moisture. Keep the medication out of the reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Follow your healthcare professional’s instructions regarding diet, exercise, and lifestyle changes while taking Fenabrate. These changes can help maximize the benefits of the medication.
• Keep regular appointments with your healthcare professional to monitor your lipid profile and overall response to treatment.
• If you miss a dose of Fenabrate, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
• maintain a healthy lifestyle, including a balanced diet, regular exercise, and avoiding smoking and excessive alcohol consumption, to further improve your lipid profile and reduce the risk of cardiovascular diseases.
• If you have any concerns or questions about Fenabrate or its use, do not hesitate to consult your healthcare professional for clarification. They are best equipped to provide personalized guidance based on your specific needs and medical history.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Fenofibrate 160mg Tablets (Health Professionals SmPC) Available at:
• Fenofibrate (Drugs.com) [Accessed 18 Jun. 2024] (online) Available at:
• fenofibrate (RX) [Accessed 12 Jun. 2024] (online) Available at:
• Fenofibrate (MedlinePlus) [Accessed 10 Jun. 2024] (online) Available at:
• Mahmoudi A, Jamialahmadi T, Johnston TP, Sahebkar A. Impact of fenofibrate on NAFLD/NASH: A genetic perspective. Drug Discov Today. 2022 Aug;27(8):2363-2372. doi: 10.1016/j.drudis.2022.05.007. Epub 2022 May 17. [Accessed 20 Jun. 2024] Available at: