Flexjak 11mg Tablet ER

Introduction

Flexjak is a prescription medication that contains the active ingredient Tofacitinib. It is available in tablet form and is commonly prescribed under the brand name Flexjak. This medication is primarily used for the treatment of certain inflammatory conditions, such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis.

Uses

Flexjak is prescribed to help manage the symptoms of various inflammatory conditions. It is commonly used to reduce joint pain, swelling, and stiffness in patients with rheumatoid arthritis and psoriatic arthritis. Additionally, it may be prescribed to help control inflammation in the colon for patients with ulcerative colitis.

Dosage and Administration

The dosage of Flexjak may vary depending on the specific condition being treated and individual patient factors. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose for adults is 11 mg taken orally once daily. However, your doctor may adjust the dosage based on your response to treatment.

These tablets are designed for extended-release, which means they release the medication slowly over time. Swallow the tablet whole with a glass of water, and do not crush, chew, or break it. It is recommended to take Flexjak with or without food, as directed by your doctor.

Mechanism of Action

Tofacitinib, the active ingredient in Flexjak, belongs to a class of medications known as Janus kinase (JAK) inhibitors. It works by blocking certain enzymes in the body that are involved in the immune system response. By inhibiting these enzymes, Tofacitinib helps to reduce inflammation and alleviate the symptoms associated with inflammatory conditions.

Side Effects

Common side effects may include headache, diarrhea, nausea, and upper respiratory tract infections. These side effects are usually mild and temporary. However, if they persist or worsen, consult your healthcare professional.

In rare cases, Flexjak may cause more serious side effects. These may include serious infections, liver problems, and changes in blood cell counts. If you experience any signs of serious side effects, such as persistent fever, yellowing of the skin or eyes, or unusual bleeding or bruising, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications may interact with Flexjak and potentially increase the risk of side effects or affect its effectiveness.

Certain medications, such as live vaccines, other JAK inhibitors, and some immunosuppressants, may have interactions with Flexjak. Additionally, avoid consuming grapefruit or grapefruit juice while taking this medication, as it may increase the levels of Tofacitinib in your body.

Precautions

Before starting treatment with Flexjak, discuss your medical history and any underlying conditions with your healthcare professional. Inform them if you have a history of infections, liver problems, or any other serious medical conditions.

This medication may lower your body’s ability to fight infections, so avoid close contact with individuals who have infections while taking Flexjak. It is also recommended to stay up to date with vaccinations as recommended by your healthcare professional.

Storage

Flexjak should be stored at room temperature, away from moisture and heat. Keep the medication in its original container and out of reach of children and pets. Do not use Flexjak if the packaging is damaged or if the tablets appear to be discolored or deteriorated.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional and take the medication as directed.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• attend regular check-ups with your healthcare professional to monitor your response to treatment and any potential side effects.
• If you experience any unusual or persistent symptoms while taking Flexjak, contact your healthcare professional for further guidance.
• Do not stop taking this medication abruptly without consulting your doctor, as it may lead to a worsening of your condition.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• XELJANZ 1 mg/mL oral solution (Health Professionals SmPC) Available at:
• Tofacitinib (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• tofacitinib tablet (RX) [Accessed 0 Jun. 2024] (online) Available at:
• Tofacitinib (MedlinePlus) [Accessed 17 Jun. 2024] (online) Available at:
• Sandborn WJ, Su C, Sands BE, D’Haens GR, Vermeire S, Schreiber S, Danese S, Feagan BG, Reinisch W, Niezychowski W, Friedman G, Lawendy N, Yu D, Woodworth D, Mukherjee A, Zhang H, Healey P, Panés J; OCTAVE Induction 1, OCTAVE Induction 2, and OCTAVE Sustain Investigators. Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis. N Engl J Med. 2017 May 4;376(18):1723-1736. doi: 10.1056/NEJMoa1606910. [Accessed 8 Jun. 2024] Available at: