Introduction
Flugesic, containing the active ingredient Flupirtine, is a medication commonly prescribed to manage moderate to severe pain in adults.
Uses
Flugesic is prescribed to alleviate pain associated with conditions such as:
- Neuropathic pain
- Postoperative pain
- Musculoskeletal pain
Dosage and Administration
- The typical dosage of Flugesic is determined by a healthcare professional based on the individual’s condition and response to treatment.
- The tablets should be taken orally with a full glass of water.
- follow the prescribed dosage and not exceed the recommended duration of use.
Mechanism of Action
Flupirtine, the active ingredient in Flugesic, works by:
- Modulating the activity of certain ion channels in the central nervous system, thereby reducing the transmission of pain signals.
Side Effects
Common side effects of Flugesic may include:
- Dizziness
- Drowsiness
- Nausea
Serious side effects that require immediate medical attention may include:
- Unusual tiredness
- Yellowing of the skin or eyes
- Persistent nausea or vomiting
Drug Interactions
Flugesic may interact with the following medications:
- CNS depressants
- MAO inhibitors
- Selective serotonin reuptake inhibitors (SSRIs)
Precautions
- Patients with a history of liver disease should exercise caution when using Flugesic.
- Avoid consuming alcohol while taking this medication as it may increase the risk of side effects.
- Inform your healthcare provider about all medications, supplements, and herbal products being used before starting Flugesic.
Storage
- Flugesic should be stored at room temperature, away from moisture and heat.
- Keep the medication out of reach of children and pets.
Patient Tips
- Do not drive or operate heavy machinery until you know how Flugesic affects you.
- attend regular follow-up appointments with your healthcare provider while using Flugesic.
- If you miss a dose, take it as soon as you remember unless it is close to the time for your next dose; do not double the dose to catch up.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Fibromyalgia – struggling with muscle pain (twitching, spasms, mind & body weak from fighting)? (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
- Devulder J. Flupirtine in pain management: pharmacological properties and clinical use. CNS Drugs. 2010 Oct;24(10):867-81. doi: 10.2165/11536230-000000000-00000. [Accessed 26 Jun. 2024] Available at:
- Szelenyi I. Flupirtine, a re-discovered drug, revisited. Inflamm Res. 2013 Mar;62(3):251-8. doi: 10.1007/s00011-013-0592-5. Epub 2013 Jan 16. [Accessed 18 Jun. 2024] Available at:
- Nickerson AJ, Rajendran VM. Flupirtine enhances NHE-3-mediated Na(+) absorption in rat colon via an ENS-dependent mechanism. Am J Physiol Gastrointest Liver Physiol. 2021 Aug 1;321(2):G185-G199. doi: 10.1152/ajpgi.00158.2021. Epub 2021 Jun 16. [Accessed 29 Jun. 2024] Available at:
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