Fos-Aprepitant 125mg Tablet

Introduction

Fos-Aprepitant is a prescription medication that contains the active ingredient Aprepitant. It is available under the brand name Fos-Aprepitant. This medication is primarily used to prevent nausea and vomiting caused by chemotherapy or surgery.

Uses

Fos-Aprepitant is prescribed to patients undergoing chemotherapy or surgery to prevent nausea and vomiting. It is commonly used in cancer patients who are receiving highly emetogenic (causing severe nausea and vomiting) chemotherapy. It helps in improving the quality of life by reducing the discomfort associated with these treatments.

Dosage and Administration

The dosage of Fos-Aprepitant may vary depending on the individual’s condition and medical history. Follow the instructions provided by your healthcare provider. Typically, the recommended dose for adults is 125 mg taken orally one hour before chemotherapy, followed by 80 mg once daily for the next two days. However, please consult your doctor for the exact dosage instructions tailored to your needs.

Mechanism of Action

Aprepitant, the active ingredient in Fos-Aprepitant, belongs to a class of medications called neurokinin-1 (NK-1) receptor antagonists. It works by blocking the action of substance P, a neurotransmitter in the brain that triggers nausea and vomiting. By inhibiting the NK-1 receptor, Aprepitant helps prevent these symptoms from occurring or reduces their severity.

Side Effects

Common side effects may include fatigue, constipation, diarrhea, and headache. These side effects are usually mild and temporary. However, if you experience any persistent or severe side effects, contact your healthcare provider for further guidance.

In rare cases, Fos-Aprepitant may cause more serious side effects, such as allergic reactions, liver problems, or changes in heart rhythm. If you develop symptoms such as rash, itching, yellowing of the eyes or skin, dark urine, or irregular heartbeat, seek immediate medical attention.

Drug Interactions

Fos-Aprepitant may interact with other medications, including certain anti-seizure medications, antifungal drugs, and some HIV medications. Inform your healthcare provider about all the medications you are currently taking, including prescription medications, over-the-counter drugs, and herbal supplements. They can provide guidance on potential interactions and adjust your medication regimen if needed.

Precautions

Before taking Fos-Aprepitant, inform your healthcare provider about any allergies or medical conditions you have, especially liver problems. Disclose all the medications you are currently taking, as certain medications may interact with Aprepitant.

Fos-Aprepitant should be used with caution in patients with a history of liver problems. Regular monitoring of liver function may be necessary during treatment. Avoid alcohol consumption while taking this medication, as it may increase the risk of liver problems.

Storage

Fos-Aprepitant should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take the medication exactly as prescribed by your healthcare provider.
• If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.
• If you experience any side effects or have any concerns, do not hesitate to contact your healthcare provider.
• attend all follow-up appointments with your doctor to monitor your progress and discuss any questions or concerns you may have.
• Remember to store the medication properly and safely, following the instructions provided.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Aprepitant 125 mg hard capsules (Health Professionals SmPC) Available at:
• Aprepitant (Drugs.com) [Accessed 0 Jun. 2024] (online) Available at:
• aprepitant (RX) [Accessed 26 Jun. 2024] (online) Available at:
• Aprepitant (MedlinePlus) [Accessed 17 Jun. 2024] (online) Available at:
• Vazirian F, Samadi S, Rahimi H, Sadeghi M, Mohammadpour AH. Aprepitant, fosaprepitant and risk of ifosfamide-induced neurotoxicity: a systematic review. Cancer Chemother Pharmacol. 2022 Jul;90(1):1-6. doi: 10.1007/s00280-022-04439-x. Epub 2022 May 30. [Accessed 4 Jun. 2024] Available at: