Introduction
Frusemene is a prescription medication that contains two active ingredients: Furosemide and Triamterene. It is commonly used to treat conditions related to fluid retention and high blood pressure.
Uses
Frusemene is primarily prescribed to manage conditions such as edema (fluid retention) and hypertension (high blood pressure). Edema can occur in various parts of the body, such as the legs, arms, or lungs, and can be caused by conditions such as heart failure or kidney disease. By reducing excess fluid in the body, Frusemene helps relieve swelling and improve breathing. Additionally, it helps lower blood pressure, reducing the strain on the heart and blood vessels.
Dosage and Administration
The dosage of Frusemene may vary depending on individual circumstances and the severity of the condition being treated. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose for adults is one tablet, taken orally, once or twice a day. Your doctor may adjust the dosage as necessary to achieve the desired therapeutic effect.
Take Frusemene with a full glass of water, preferably with food, to help minimize stomach upset. Do not crush or chew the tablets; swallow them whole.
Mechanism of Action
Frusemene contains two active ingredients: Furosemide and Triamterene. Furosemide is a diuretic, commonly known as a “water pill,” that works by increasing the amount of urine produced by the kidneys. This helps remove excess fluid and salt from the body, reducing swelling and lowering blood pressure.
Triamterene is a potassium-sparing diuretic that works by preventing the body from losing too much potassium while eliminating excess fluid. It helps maintain the balance of potassium and sodium in the body, which is important for proper functioning of the heart, muscles, and nerves.
Side Effects
Common side effects may include increased urination, dizziness, headache, or upset stomach. These side effects are usually mild and temporary. If any of these side effects persist or worsen, consult your healthcare professional.
In rare cases, Frusemene may cause more serious side effects, such as allergic reactions, severe dizziness, irregular heartbeat, or muscle weakness. If you experience any of these symptoms, seek immediate medical attention.
Drug Interactions
Frusemene may interact with certain medications and substances, potentially affecting its effectiveness or increasing the risk of side effects. Inform your healthcare professional about all the medications, supplements, and herbal products you are currently taking.
Some examples of medications that may interact with Frusemene include other diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), lithium, certain antibiotics, and certain blood pressure medications. These are not an exhaustive list, so consult your healthcare professional for a comprehensive review of potential drug interactions.
Precautions
Before taking Frusemene, inform your healthcare professional if you have any known allergies, especially to sulfa drugs. Additionally, disclose your medical history, including any kidney or liver problems, diabetes, gout, or urinary problems.
Frusemene may not be suitable for everyone. It is contraindicated in patients who are allergic to Furosemide, Triamterene, or any of the inactive ingredients in the medication. It is also not recommended for use during pregnancy or while breastfeeding.
Storage
Frusemene should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of the reach of children and pets. Do not use the medication if it has expired or if the tablets appear discolored or damaged.
Patient Tips
- Take Frusemene exactly as prescribed by your healthcare professional. Do not alter the dosage or stop taking the medication without consulting them first.
- maintain a balanced diet and avoid excessive consumption of salt while taking Frusemene. Follow any dietary recommendations provided by your healthcare professional.
- Stay well-hydrated while taking this medication, unless otherwise advised by your healthcare professional.
- If you miss a dose of Frusemene, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- If you have any concerns or questions about your medication, reach out to your healthcare professional for clarification. They are the best resource for personalized advice and guidance.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Furosemide: medicine to treat high blood pressure and oedema (NHS UK) [Accessed 24 Jun. 2024] (online) Available at:
- Co-Amilofruse 10mg/80mg Tablets (Health Professionals SmPC) Available at:
- Furosemide (Drugs.com) [Accessed 14 Jun. 2024] (online) Available at:
- furosemide (lasix) (RX) [Accessed 16 Jun. 2024] (online) Available at:
- Furosemide Injection (MedlinePlus) [Accessed 23 Jun. 2024] (online) Available at:
- Ponto LL, Schoenwald RD. Furosemide (frusemide). A pharmacokinetic/pharmacodynamic review (Part I). Clin Pharmacokinet. 1990 May;18(5):381-408. doi: 10.2165/00003088-199018050-00004. [Accessed 11 Jun. 2024] Available at:
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