Introduction
Gabazil-AT SR is a prescription medication that contains two active ingredients: Gabapentin and Amitriptyline. It is commonly used to treat certain types of nerve pain and depression.
Uses
Gabazil-AT SR is primarily prescribed to manage nerve pain caused by conditions such as diabetic neuropathy and postherpetic neuralgia. Additionally, it may be used to alleviate symptoms of depression in individuals who also experience chronic pain.
Dosage and Administration
The dosage of Gabazil-AT SR will vary depending on the individual’s specific condition and medical history. Follow the instructions provided by your healthcare professional. Generally, the initial dose may be low and gradually increased to achieve the desired therapeutic effect. The tablets should be taken orally, with or without food, as directed by your doctor.
Mechanism of Action
Gabapentin, one of the active ingredients in Gabazil-AT SR, works by reducing abnormal electrical activity in the brain and altering the way nerves send pain signals. Amitriptyline, the other active ingredient, is a tricyclic antidepressant that helps regulate the balance of certain chemicals in the brain, thereby improving mood and reducing pain perception.
Side Effects
Common side effects of Gabazil-AT SR may include drowsiness, dizziness, dry mouth, constipation, blurred vision, and weight gain. These side effects are generally mild and may subside as your body adjusts to the medication. However, if any of these side effects persist or worsen, consult your healthcare professional.
Serious side effects are rare but can occur. Contact your doctor immediately if you experience any unusual changes in mood or behavior, worsening depression, suicidal thoughts, difficulty urinating, rapid or irregular heartbeat, rash, or allergic reactions such as swelling or difficulty breathing.
Drug Interactions
Gabazil-AT SR may interact with certain medications, including but not limited to central nervous system depressants, antacids, and monoamine oxidase inhibitors (MAOIs). Inform your healthcare professional about all the medications you are currently taking to avoid potential interactions. They can advise on any necessary adjustments to your medication regimen.
Precautions
Before taking Gabazil-AT SR, inform your healthcare professional about any pre-existing medical conditions, including a history of seizures, heart problems, liver or kidney disease, or urinary retention. Additionally, disclose any medications, supplements, or herbal products you are currently taking to ensure they do not interact negatively with Gabazil-AT SR.
Gabazil-AT SR may cause drowsiness and dizziness, so avoid activities that require alertness until you know how the medication affects you. Alcohol and certain medications may intensify these effects, so it is advisable to avoid or limit alcohol consumption while taking this medication.
Storage
Gabazil-AT SR should be stored at room temperature, away from excess heat, moisture, and light. Keep the medication out of reach of children and pets. Do not use this medication if it has expired or if the packaging is damaged.
Patient Tips
- Take Gabazil-AT SR exactly as prescribed by your healthcare professional. Do not adjust the dosage or stop taking the medication without consulting your doctor.
- If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
- It may take some time for Gabazil-AT SR to reach its full effectiveness. Be patient and continue taking the medication as directed.
- If you have any questions or concerns about Gabazil-AT SR, don’t hesitate to reach out to your healthcare professional. They are there to provide guidance and support throughout your treatment journey.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Amitriptyline: a medicine to treat pain and prevent migraine (NHS UK) [Accessed 25 Jun. 2024] (online) Available at:
- Amitriptyline 10 mg Film-Coated Tablets (Health Professionals SmPC) Available at:
- Amitriptyline (Drugs.com) [Accessed 14 Jun. 2024] (online) Available at:
- amitriptyline hcl (RX) [Accessed 25 Jun. 2024] (online) Available at:
- Amitriptyline (MedlinePlus) [Accessed 3 Jun. 2024] (online) Available at:
- McClure EW, Daniels RN. Classics in Chemical Neuroscience: Amitriptyline. ACS Chem Neurosci. 2021 Feb 3;12(3):354-362. doi: 10.1021/acschemneuro.0c00467. Epub 2021 Jan 13. [Accessed 12 Jun. 2024] Available at:
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