Gastoseal Capsule SR

Introduction

Gastoseal SR is a prescription medication that combines two active ingredients: Diclofenac and Rabeprazole. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that helps to reduce pain, inflammation, and swelling. Rabeprazole belongs to a class of medications known as proton pump inhibitors (PPIs) and helps to reduce the production of stomach acid. This combination medication is primarily used to provide relief from pain and inflammation associated with certain conditions, while also protecting the stomach from potential damage caused by NSAIDs.

Uses

Gastoseal SR is prescribed for the treatment of various conditions, including:

• Rheumatoid arthritis: It helps to reduce pain, swelling, and joint stiffness associated with this chronic inflammatory disease.
• Osteoarthritis: It helps to relieve pain and improve joint function in individuals with this degenerative joint condition.
• Ankylosing spondylitis: It helps to reduce pain, stiffness, and inflammation in the spine and other joints.
• Gout: It can help alleviate the pain and inflammation associated with acute gout attacks.
• Dyspepsia: It helps to relieve symptoms such as stomach pain, heartburn, and indigestion caused by excessive stomach acid.

Dosage and Administration

follow the dosage instructions provided by your healthcare professional. Gastoseal SR is typically taken orally with a glass of water, preferably with or after meals. Swallow the capsule whole and do not crush, chew, or break it.

The recommended dosage may vary depending on the specific condition being treated, the severity of symptoms, and individual factors. Your healthcare professional will determine the appropriate dose for you. It is important not to exceed the prescribed dosage and to take the medication for the prescribed duration.

Mechanism of Action

Gastoseal SR works by combining the effects of its two active ingredients, Diclofenac and Rabeprazole.

• Diclofenac: It works by inhibiting the production of certain chemicals in the body called prostaglandins, which are involved in the inflammatory process. By reducing the production of these chemicals, Diclofenac helps to alleviate pain, inflammation, and swelling.
• Rabeprazole: It works by blocking the action of an enzyme in the stomach called the proton pump, which is responsible for producing stomach acid. By reducing the production of stomach acid, Rabeprazole helps to protect the stomach lining from potential damage caused by NSAIDs.

Side Effects

be aware of these potential side effects, although not everyone will experience them. Common side effects may include:

• Upset stomach
• Nausea
• Diarrhea
• Headache

If any of these side effects persist or worsen, consult your healthcare professional.

In rare cases, Gastoseal SR may cause more serious side effects. These can include:

• Allergic reactions
• Severe stomach pain
• Black or bloody stools
• Chest pain or shortness of breath

If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Gastoseal SR may interact with certain medications, including:

• Anticoagulants (blood thinners) such as warfarin
• Antiplatelet drugs such as aspirin or clopidogrel
• Corticosteroids
• Methotrexate
• Selective serotonin reuptake inhibitors (SSRIs)

inform your healthcare professional about all medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions.

Precautions

Before taking Gastoseal SR, consider the following precautions:

• Allergies: Inform your healthcare professional if you have any known allergies to Diclofenac, Rabeprazole, or any other medications.
• Medical Conditions: Inform your healthcare professional if you have a history of stomach ulcers, bleeding disorders, liver or kidney disease, or any other medical conditions.
• Pregnancy and Breastfeeding: Gastoseal SR may not be suitable during pregnancy or while breastfeeding. Consult your healthcare professional for guidance.

Storage

Gastoseal SR should be stored at room temperature, away from moisture and heat. Keep the medication out of the reach of children and pets. Do not use the medication after the expiration date printed on the packaging.

Patient Tips

Here are some additional tips to keep in mind when using Gastoseal SR:

• Take the medication as prescribed by your healthcare professional.
• If you forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take more than the recommended dose to make up for a missed dose.
• Avoid consuming alcohol while taking Gastoseal SR, as it may increase the risk of stomach irritation.
• If you experience any unusual symptoms or have concerns about the medication, contact your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

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• Diclofenac 2.32% gel (Health Professionals SmPC) Available at:
• Diclofenac (Drugs.com) [Accessed 28 Jun. 2024] (online) Available at:
• aleve (diclofenac) 1 % topical gel non-steroidal anti-inflammatory agents (nsaid) (OTC) [Accessed 20 Jun. 2024] (online) Available at:
• Diclofenac Topical (arthritis pain) [Accessed 5 Jun. 2024] (online) Available at:
• Hamed R, Mahmoud NN, Alnadi SH, Alkilani AZ, Hussein G. Diclofenac diethylamine nanosystems-loaded bigels for topical delivery: development, rheological characterization, and release studies. Drug Dev Ind Pharm. 2020 Oct;46(10):1705-1715. doi: 10.1080/03639045.2020.1820038. Epub 2020 Sep 18. [Accessed 23 Jun. 2024] Available at: