Glarzen 100IU/ml Dispopen 2

Introduction

Glarzen is a medication that contains the active ingredient Insulin Glargine. Insulin Glargine is a long-acting insulin analog that helps to control blood sugar levels in people with diabetes. It is available under the brand name Glarzen.

Uses

Glarzen is primarily prescribed for the treatment of diabetes mellitus in adults. It is used to help manage blood sugar levels in individuals with type 1 diabetes, who cannot produce enough insulin, as well as in individuals with type 2 diabetes, who do not produce enough insulin or do not use insulin effectively.

Dosage and Administration

Glarzen is administered through subcutaneous injection, typically once daily. The dosage will depend on individual factors such as the patient’s age, weight, and blood sugar levels. Follow the dosage instructions provided by your healthcare professional.

Mechanism of Action

Insulin Glargine, the active ingredient in Glarzen, works by mimicking the effects of natural insulin in the body. It helps to regulate blood sugar levels by promoting the uptake of glucose from the blood into the cells, where it can be used for energy. Insulin Glargine has a long duration of action, providing a steady release of insulin over an extended period of time.

Side Effects

Common side effects may include injection site reactions such as redness, itching, or pain. These side effects are usually mild and temporary. However, if they persist or worsen, inform your healthcare professional.

Serious side effects are rare but may include allergic reactions, experiencing low blood sugar levels (hypoglycemia), or high blood sugar levels (hyperglycemia). If you experience symptoms such as dizziness, sweating, confusion, or rapid heartbeat, or if you notice persistent high blood sugar levels, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, as they may interact with Glarzen. Some common drug interactions include certain oral medications that may affect blood sugar levels, such as beta-blockers, corticosteroids, or diuretics. Your healthcare professional will guide you on how to manage these interactions and adjust your medication regimen accordingly.

Precautions

Before using Glarzen, inform your healthcare professional about any medical conditions you have, especially if you have a history of kidney or liver disease or any allergies. Disclose all medications you are currently taking to avoid potential drug interactions.

Glarzen should not be used if you are allergic to Insulin Glargine or any of the other ingredients in the medication. Follow your healthcare professional’s instructions regarding the use of this medication and to regularly monitor your blood sugar levels.

Storage

Glarzen should be stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Once opened, the vial should be stored at room temperature (not exceeding 30°C or 86°F) and used within 28 days. Keep the medication out of the reach of children and pets.

Patient Tips

• Always follow your healthcare professional’s instructions regarding the use of Glarzen.
• Properly rotate injection sites to avoid irritation or changes in the skin.
• Regularly monitor your blood sugar levels as directed by your healthcare professional.
• Be aware of the signs and symptoms of low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia) and seek medical attention if necessary.
• Carry a form of identification indicating that you have diabetes and are using insulin.
• Do not change your dose or stop using Glarzen without consulting your healthcare professional.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Type 1 diabetes – Managing insulin (NHS UK) [Accessed 6 Jun. 2024] (online) Available at:
• ABASAGLAR 100 units/mL KwikPen solution for injection in a pre-filled pen (Health Professionals SmPC) Available at:
• Insulin Glargine (Drugs.com) [Accessed 25 Jun. 2024] (online) Available at:
• insulin glargine (u-100) 100 unit/ml subcutaneous solution intermediate-, long-acting, and combination insulins (RX) [Accessed 17 Jun. 2024] (online) Available at:
• Insulin Glargine (rDNA origin) Injection [Accessed 18 Jun. 2024] (online) Available at:
• Rosenstock J, Bain SC, Gowda A, Jódar E, Liang B, Lingvay I, Nishida T, Trevisan R, Mosenzon O; ONWARDS 1 Trial Investigators. Weekly Icodec versus Daily Glargine U100 in Type 2 Diabetes without Previous Insulin. N Engl J Med. 2023 Jul 27;389(4):297-308. doi: 10.1056/NEJMoa2303208. Epub 2023 Jun 24. [Accessed 13 Jun. 2024] Available at: