Gln 2.6 Tablet SR

Introduction

Gln is a medication that contains Nitroglycerin as its active ingredient. It is available in the form of extended-release tablets.

Uses

Gln is primarily prescribed for the treatment of angina pectoris, a condition characterized by chest pain or discomfort caused by reduced blood flow to the heart. It helps to relieve the symptoms of angina and improve exercise tolerance.

Dosage and Administration

The dosage of Gln may vary depending on individual patient factors and the severity of the condition. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose is one tablet (2.5 mg) taken orally once daily. The dose may be adjusted based on your response to the medication.

Gln should be swallowed whole and not chewed, crushed, or broken. It is designed to release the medication slowly over time to provide a consistent effect. It is important not to exceed the prescribed dose or suddenly stop taking the medication without consulting your healthcare professional.

Mechanism of Action

Nitroglycerin, the active ingredient in Gln, works by relaxing and dilating the blood vessels, particularly those supplying the heart. This helps to increase blood flow and reduce the workload on the heart, relieving the symptoms of angina. Nitroglycerin is converted to nitric oxide in the body, which then activates an enzyme called guanylate cyclase. This enzyme promotes the production of cyclic guanosine monophosphate (cGMP), a substance that relaxes the smooth muscles in the blood vessels.

Side Effects

Common side effects may include headaches, dizziness, flushing, and low blood pressure. These side effects are usually mild and temporary.

In rare cases, serious side effects may occur, such as a rapid or irregular heartbeat, fainting, or severe allergic reactions. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Gln may interact with certain medications, supplements, or substances, potentially leading to adverse effects or reducing the effectiveness of the medication. Inform your healthcare professional about all the medications you are currently taking, including over-the-counter drugs and herbal supplements.

Some medications that may interact with Gln include other medications for the treatment of erectile dysfunction, certain blood pressure medications, and medications that increase bleeding risk. Your healthcare professional can provide you with more specific information on potential drug interactions.

Precautions

Before starting Gln, inform your healthcare professional about any medical conditions you have, especially if you have low blood pressure, a history of heart attack or heart failure, or if you are taking medications for erectile dysfunction.

Gln is contraindicated in patients who are allergic to nitroglycerin or any of the other ingredients in the medication. It should also be used with caution in patients with certain types of glaucoma or increased intracranial pressure.

Storage

Gln should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Do not use the medication after the expiration date printed on the packaging.

Patient Tips

• Take Gln exactly as prescribed by your healthcare professional. Do not change the dose or stop taking the medication without consulting your doctor.
• If you experience chest pain while taking Gln, follow your doctor’s instructions for using sublingual nitroglycerin to relieve the pain.
• Avoid drinking alcohol while taking Gln, as it may increase the risk of side effects such as dizziness or low blood pressure.
• If you have any questions or concerns about Gln or its use, consult your healthcare professional for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Nitroglycerin rectal (Drugs.com) [Accessed 7 Jun. 2024] (online) Available at:
• nitroglycerin (RX) [Accessed 17 Jun. 2024] (online) Available at:
• Nitroglycerin Topical (MedlinePlus) [Accessed 15 Jun. 2024] (online) Available at:
• Todd PA, Goa KL, Langtry HD. Transdermal nitroglycerin (glyceryl trinitrate). A review of its pharmacology and therapeutic use. Drugs. 1990 Dec;40(6):880-902. doi: 10.2165/00003495-199040060-00009. [Accessed 17 Jun. 2024] Available at: