Glura MP 1000 Tablet SR

Introduction

Glura MP is a prescription medication that combines three active ingredients: Metformin, Pioglitazone, and Sitagliptin. It is available in tablet form and is commonly used to manage blood sugar levels in individuals with type 2 diabetes.

Uses

Glura MP is primarily prescribed to treat type 2 diabetes. It helps lower blood sugar levels by improving insulin sensitivity, reducing the production of glucose in the liver, and increasing the release of insulin from the pancreas. This medication is often used in conjunction with a healthy diet and regular exercise to effectively manage diabetes.

Dosage and Administration

The dosage of Glura MP may vary depending on individual needs and the guidance of a healthcare professional. It is typically taken orally, with or without food. The tablets should be swallowed whole and not crushed or chewed. Follow the prescribed dosage and administration instructions provided by your healthcare provider.

Mechanism of Action

Metformin, Pioglitazone, and Sitagliptin work together to help control blood sugar levels in different ways. Metformin reduces the production of glucose in the liver and improves the body’s response to insulin. Pioglitazone helps improve insulin sensitivity, allowing the body to use insulin more effectively. Sitagliptin increases the release of insulin from the pancreas and reduces the production of glucose. By targeting multiple pathways involved in blood sugar regulation, Glura MP helps to achieve better glycemic control.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, stomach upset, and headache. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, seek medical attention.

In rare cases, Glura MP may cause more serious side effects such as lactic acidosis (a buildup of lactic acid in the blood), which can be life-threatening. Symptoms of lactic acidosis may include weakness, tiredness, muscle pain, difficulty breathing, and stomach discomfort. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

Glura MP may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Inform your healthcare provider of all the medications you are taking to avoid any potential interactions. Some common drug interactions include:

• Certain medications used to treat heart conditions, such as digoxin or beta-blockers, may interact with Glura MP.
• Other diabetes medications, such as insulin or sulfonylureas, may require dosage adjustments when taken with Glura MP.
• Some medications used to treat high blood pressure, such as ACE inhibitors or diuretics, may interact with Glura MP.

Consult your healthcare provider or pharmacist before starting or stopping any medications while taking Glura MP.

Precautions

Before starting Glura MP, inform your healthcare provider about any pre-existing medical conditions, including kidney or liver disease, heart problems, or a history of lactic acidosis. Additionally, inform your healthcare provider about any allergies you may have to medications or other substances.

Glura MP is not recommended for individuals with severe kidney or liver impairment. Follow the dosage instructions provided by your healthcare provider and not exceed the prescribed dose.

Alcohol consumption while taking Glura MP should be avoided or limited, as it may increase the risk of lactic acidosis.

Storage

Glura MP should be stored at room temperature, away from excessive heat, moisture, and light. Keep the medication in its original packaging, and ensure it is out of reach of children and pets. Do not use the medication if it has reached its expiration date. If you have any unused or expired medication, dispose of it properly according to local regulations.

Patient Tips

• Take Glura MP exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your healthcare provider first.
• Follow a healthy diet and exercise regularly while taking Glura MP to optimize its effectiveness in managing your blood sugar levels.
• Monitor your blood sugar levels regularly as directed by your healthcare provider.
• If you experience any bothersome or persistent side effects, inform your healthcare provider.
• Keep all follow-up appointments with your healthcare provider to monitor your progress and make any necessary adjustments to your treatment plan.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metformin: a medicine to treat type 2 diabetes (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Competact 15 mg/850 mg film-coated tablets (Health Professionals SmPC) Available at:
• Metformin (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• metformin (RX) [Accessed 21 Jun. 2024] (online) Available at:
• Metformin (MedlinePlus) [Accessed 2 Jun. 2024] (online) Available at:
• LaMoia TE, Shulman GI. Cellular and Molecular Mechanisms of Metformin Action. Endocr Rev. 2021 Jan 28;42(1):77-96. doi: 10.1210/endrev/bnaa023. [Accessed 21 Jun. 2024] Available at: