Grandem Syrup

Introduction

Grandem is a prescription medication that contains the active ingredient Granisetron. It is available in syrup form and is primarily used for the treatment of nausea and vomiting associated with chemotherapy and radiation therapy.

Uses

Grandem is prescribed to manage nausea and vomiting caused by chemotherapy and radiation therapy. It is commonly used in cancer patients undergoing these treatments, as these therapies often result in severe nausea and vomiting. By reducing these symptoms, Grandem can help improve the quality of life for patients undergoing cancer treatment.

Dosage and Administration

The recommended dosage of Grandem may vary depending on the individual patient and their specific needs. Follow the instructions provided by your healthcare provider or the directions on the prescription label. Typically, the syrup is taken orally, usually once a day, with or without food.

Mechanism of Action

Grandem contains the active ingredient Granisetron, which belongs to a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a substance in the body that can trigger nausea and vomiting. By blocking the activity of serotonin, Grandem helps to prevent and reduce these symptoms.

Side Effects

Common side effects may include headache, constipation, diarrhea, and stomach pain. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, seek medical attention.

Serious side effects are rare but may include allergic reactions, irregular heartbeat, and chest pain. If you experience any of these symptoms, seek immediate medical attention.

Drug Interactions

Grandem may interact with certain medications, including other medications that affect serotonin levels in the body. Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. They can determine if any potential drug interactions may occur.

Precautions

Before taking Grandem, inform your healthcare provider about any medical conditions you have, especially if you have a history of irregular heartbeat or other heart problems. Additionally, inform your healthcare provider about any allergies you may have, as Grandem may contain inactive ingredients that can cause allergic reactions.

Note that Grandem is not recommended for use during pregnancy unless specifically prescribed by your healthcare provider. It is also not recommended for use while breastfeeding.

Storage

Patient Tips

• Take Grandem exactly as prescribed by your healthcare provider. Do not exceed the recommended dosage or take it more frequently than instructed.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
• Avoid consuming alcohol while taking Grandem, as it may increase the risk of side effects.
• If you have any concerns or questions about your medication, do not hesitate to consult your healthcare provider for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Granisetron 1 mg film-coated tablets (Health Professionals SmPC) Available at:
• Granisetron (Drugs.com) [Accessed 23 Jun. 2024] (online) Available at:
• granisetron (pf) 100 mcg/ml (0.1 mg/ml) intravenous solution (RX) [Accessed 4 Jun. 2024] (online) Available at:
• Granisetron Injection (MedlinePlus) [Accessed 27 Jun. 2024] (online) Available at:
• Duggan ST, Curran MP. Transdermal granisetron. Drugs. 2009;69(18):2597-605. doi: 10.2165/11202780-000000000-00000. [Accessed 14 Jun. 2024] Available at: