Hansepran 100 Capsule

Introduction

Hansepran is a prescription medication that contains the active ingredient Clofazimine. It is available in capsule form and is primarily used for the treatment of certain bacterial infections.

Uses

Hansepran is prescribed to treat various conditions caused by bacteria, including leprosy (Hansen’s disease). It is an important component of multi-drug therapy for leprosy and helps to eliminate the bacteria responsible for the disease.

Dosage and Administration

The dosage of Hansepran will depend on the specific condition being treated and the individual patient. Follow the instructions provided by your healthcare provider. Generally, the recommended dosage for adults is 100 to 300 milligrams per day, taken orally in divided doses. The capsule should be swallowed whole with a glass of water or with food to minimize stomach upset.

Mechanism of Action

Clofazimine, the active ingredient in Hansepran, works by interfering with the growth and reproduction of bacteria. It binds to the DNA of the bacteria, preventing them from replicating and causing further infection. By inhibiting bacterial growth, Clofazimine helps to control the progression of leprosy and other bacterial infections.

Side Effects

Common side effects may include discoloration of the skin (reddish-brown or black), dryness or scaling of the skin, gastrointestinal disturbances (such as nausea, vomiting, or abdominal pain), and changes in appetite. These side effects are generally mild and may subside as the body adjusts to the medication.

However, be aware of more serious side effects that may occur. These can include severe skin reactions, such as blistering or peeling, jaundice (yellowing of the skin or eyes), and signs of an allergic reaction (such as rash, itching, swelling, or difficulty breathing). If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

Hansepran may interact with other medications, so inform your healthcare provider about all the medications you are currently taking. Specifically, it may interact with drugs that affect the liver, such as certain antibiotics and antiretroviral medications. These interactions can potentially increase the risk of side effects or affect the effectiveness of the medication. Your healthcare provider will be able to assess any potential interactions and adjust your treatment plan accordingly.

Precautions

Before taking Hansepran, inform your healthcare provider about any medical conditions you have, especially liver or kidney disease. Additionally, inform your healthcare provider about any allergies you have, as well as any other medications or supplements you are taking.

Hansepran should not be used during pregnancy, as it may cause harm to the unborn baby. Avoid breastfeeding while taking this medication, as it may pass into breast milk.

Storage

Hansepran should be stored at room temperature, away from direct sunlight and moisture. Keep the medication in its original container and out of reach of children. Do not use Hansepran if it has expired or if the capsules appear damaged or discolored.

Patient Tips

• Take Hansepran exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting your doctor.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• complete the full course of treatment prescribed by your healthcare provider, even if you start feeling better before the treatment is finished.
• If you experience any unusual or bothersome side effects, or if you have any questions or concerns about your treatment, contact your healthcare provider for further guidance.
• Follow good hygiene practices to help prevent the spread of leprosy or any other bacterial infections. This includes regular handwashing, covering your mouth and nose when coughing or sneezing, and avoiding close contact with individuals who are sick.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Clofazimine (Drugs.com) [Accessed 19 Jun. 2024] (online) Available at:
• Leprosy (MedlinePlus) [Accessed 9 Jun. 2024] (online) Available at:
• Xu J, Koval A, Katanaev VL. Clofazimine: A journey of a drug. Biomed Pharmacother. 2023 Nov;167:115539. doi: 10.1016/j.biopha.2023.115539. Epub 2023 Sep 22. [Accessed 0 Jun. 2024] Available at:
• Zhang J, Dong J. Clofazimine-associated enteropathy. Gastrointest Endosc. 2024 Jun;99(6):1070-1071. doi: 10.1016/j.gie.2024.01.038. Epub 2024 Jan 30. [Accessed 7 Jun. 2024] Available at: