Infimab Injection

Introduction

Infimab is a medication that contains the active ingredient Infliximab. It is commonly known by its generic name, Infliximab.

Uses

Infimab is prescribed for several conditions, including:

• Rheumatoid arthritis: It is used to reduce the signs and symptoms of rheumatoid arthritis, such as joint pain, swelling, and stiffness.
• Crohn’s disease: It is prescribed to treat moderate to severe Crohn’s disease in adults and children.
• Ulcerative colitis: It is used to induce and maintain remission in adults and children with moderate to severe ulcerative colitis.
• Psoriasis: It is prescribed for the treatment of moderate to severe plaque psoriasis in adult patients.

Dosage and Administration

Infimab is administered by a healthcare professional through an intravenous (IV) infusion. The dosage and frequency of administration may vary depending on the specific condition being treated. Follow the instructions provided by your healthcare provider.

Mechanism of Action

Infliximab, the active ingredient in Infimab, belongs to a class of medications called tumor necrosis factor (TNF) inhibitors. It works by inhibiting the activity of TNF, a protein in the body that plays a role in causing inflammation. By blocking the action of TNF, Infimab helps to reduce inflammation and the symptoms associated with the conditions it is prescribed for.

Side Effects

Common side effects may include:

• Headache
• Nausea
• Fatigue
• Upper respiratory tract infection
• Injection site reactions

Serious side effects are rare but may include:

• Serious infections: Infimab may increase the risk of developing serious infections. Contact your healthcare provider if you experience signs of infection such as fever, chills, or worsening symptoms.
• Allergic reactions: Seek immediate medical attention if you experience symptoms of an allergic reaction, such as difficulty breathing, swelling of the face or throat, or rash.

If you experience any side effects while using Infimab, consult your healthcare provider.

Drug Interactions

Infimab may interact with other medications. Inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions may include:

• Live vaccines: Infimab may affect the effectiveness of live vaccines. Consult your healthcare provider before receiving any vaccinations.
• Immunosuppressive medications: Combining Infimab with other immunosuppressive medications may increase the risk of infections. Your healthcare provider will monitor you closely if you are taking multiple immunosuppressive medications.

Discuss potential drug interactions with your healthcare provider to ensure the safe and effective use of Infimab.

Precautions

Before using Infimab, consider the following precautions:

• Contraindications: Infimab should not be used in individuals with known hypersensitivity to Infliximab or any of its components.
• Infections: Inform your healthcare provider if you have a history of recurrent infections or any signs of an infection before starting Infimab.
• Cancer: Patients with a history of cancer or those currently undergoing cancer treatment should discuss the risks and benefits of using Infimab with their healthcare provider.

Discuss your medical history and any potential risks with your healthcare provider before using Infimab.

Storage

Infimab should be stored in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Keep it in the original packaging to protect it from light. Do not use Infimab if it has been frozen or if it has expired.

Patient Tips

Here are a few additional tips for patients using Infimab:

• Follow the recommended dosage and administration instructions provided by your healthcare provider.
• If you miss a dose, contact your healthcare provider for further instructions.
• Inform your healthcare provider about any new or worsening symptoms.
• Attend all scheduled appointments for monitoring and follow-up.
• If you have any concerns or questions about the medication, don’t hesitate to reach out to your healthcare provider.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Flixabi 100 mg powder for concentrate for solution for infusion (Health Professionals SmPC) Available at:
• Infliximab (Drugs.com) [Accessed 7 Jun. 2024] (online) Available at:
• infliximab 100 mg intravenous solution inflammatory bowel agents (RX) [Accessed 30 Jun. 2024] (online) Available at:
• Infliximab Injection (MedlinePlus) [Accessed 20 Jun. 2024] (online) Available at:
• Lichtenstein L, Ron Y, Kivity S, Ben-Horin S, Israeli E, Fraser GM, Dotan I, Chowers Y, Confino-Cohen R, Weiss B. Infliximab-Related Infusion Reactions: Systematic Review. J Crohns Colitis. 2015 Sep;9(9):806-15. doi: 10.1093/ecco-jcc/jjv096. Epub 2015 Jun 19. [Accessed 4 Jun. 2024] Available at: