Isuvaz 200mg Injection

$356.40

1 Vial, 1 Injection per vial

Active ingredient: Isavuconazole (200mg)

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Isuvaz 200mg Injection
$356.40

Introduction

Isuvaz is a prescription medication that contains the active ingredient Isavuconazole. It is available in the form of an injection and is used for the treatment of certain fungal infections.

Uses

Isuvaz is prescribed for the treatment of invasive aspergillosis and invasive mucormycosis in adult patients. These are serious fungal infections that can affect different parts of the body, including the lungs, sinuses, and brain.

Dosage and Administration

The dosage of Isuvaz will depend on the specific fungal infection being treated, as well as the patient’s overall health and medical history. Follow the instructions provided by your healthcare professional or as indicated on the product label. Isuvaz is administered by a healthcare professional through a vein (intravenous infusion).

Mechanism of Action

Isavuconazole, the active ingredient in Isuvaz, belongs to a class of antifungal medications known as triazoles. It works by inhibiting the growth and reproduction of the fungi responsible for the infection. Isavuconazole interferes with the synthesis of ergosterol, an essential component of the fungal cell membrane, leading to the disruption of fungal cell growth and ultimately, their elimination.

Side Effects

be aware of both common and serious side effects and to seek medical attention if they occur. Common side effects may include nausea, vomiting, diarrhea, headache, and abnormal liver function tests. Serious side effects may include severe allergic reactions, liver problems, and kidney problems. If you experience any severe or persistent side effects, contact your healthcare provider immediately.

Drug Interactions

Isuvaz may interact with other medications, including certain anticoagulants, anticonvulsants, immunosuppressants, and drugs that affect the heart rhythm. Inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. They can assess any potential drug interactions and adjust your treatment plan accordingly.

Precautions

Before using Isuvaz, let your healthcare professional know if you have any allergies, especially to azole antifungal medications. Additionally, inform them about any medical conditions you have, such as liver or kidney problems. Isuvaz should be used with caution in pregnant or breastfeeding women, as well as in patients with certain heart conditions. Follow your healthcare professional’s guidance and discuss any potential risks or concerns.

Storage

Patient Tips

  • Follow the prescribed dosage: Take Isuvaz exactly as prescribed by your healthcare professional. Do not change the dosage or stop the medication without consulting them.
  • Complete the full course of treatment: complete the full course of treatment, even if you start feeling better. This helps ensure that the infection is completely treated and reduces the risk of recurrence.
  • Attend follow-up appointments: Regularly follow up with your healthcare professional to monitor your progress and discuss any concerns or side effects.
  • Take precautions to prevent infections: To reduce the risk of fungal infections, practice good hygiene, avoid close contact with individuals who have infections, and follow any additional precautions recommended by your healthcare professional.
  • Inform your healthcare professional: Always inform your healthcare professional about any new symptoms or changes in your health while using Isuvaz. They can assess your condition and make any necessary adjustments to your treatment plan.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

  • Isavuconazole use while Breastfeeding (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
  • Mucormycosis (MedlinePlus) [Accessed 1 Jun. 2024] (online) Available at:
  • Maertens JA, Raad II, Marr KA, Patterson TF, Kontoyiannis DP, Cornely OA, Bow EJ, Rahav G, Neofytos D, Aoun M, Baddley JW, Giladi M, Heinz WJ, Herbrecht R, Hope W, Karthaus M, Lee DG, Lortholary O, Morrison VA, Oren I, Selleslag D, Shoham S, Thompson GR 3rd, Lee M, Maher RM, Schmitt-Hoffmann AH, Zeiher B, Ullmann AJ. Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3, randomised-controlled, non-inferiority trial. Lancet. 2016 Feb 20;387(10020):760-9. doi: 10.1016/S0140-6736(15)01159-9. Epub 2015 Dec 10. [Accessed 29 Jun. 2024] Available at:
  • Kullberg BJ, Viscoli C, Pappas PG, Vazquez J, Ostrosky-Zeichner L, Rotstein C, Sobel JD, Herbrecht R, Rahav G, Jaruratanasirikul S, Chetchotisakd P, Van Wijngaerden E, De Waele J, Lademacher C, Engelhardt M, Kovanda L, Croos-Dabrera R, Fredericks C, Thompson GR. Isavuconazole Versus Caspofungin in the Treatment of Candidemia and Other Invasive Candida Infections: The ACTIVE Trial. Clin Infect Dis. 2019 May 30;68(12):1981-1989. doi: 10.1093/cid/ciy827. [Accessed 10 Jun. 2024] Available at:

Additional information

Active ingredients

Strength

Isavuconazole (200mg)

Dosage form

Injection

Indications

Invasive Aspergillosis

Brand

Manufacturer

Manufacturer's location

Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

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