Itraconol TR 100mg/250mg Tablet

Introduction

Itraconol TR is a prescription medication that combines two active ingredients, Itraconazole and Terbinafine. It is commonly used to treat fungal infections of the skin, hair, and nails. This medication is available under the brand name Itraconol TR.

Uses

Itraconol TR is primarily prescribed for the treatment of fungal infections, including:

• Athlete’s foot (Tinea pedis)
• Ringworm (Tinea corporis)
• Jock itch (Tinea cruris)
• Fungal nail infections (Onychomycosis)

note that this medication is effective against specific types of fungi, and your healthcare provider will determine if it is the appropriate treatment option for your specific condition.

Dosage and Administration

The dosage of Itraconol TR will vary depending on the severity of the fungal infection and individual patient factors. Follow the instructions provided by your healthcare provider. Generally, the recommended dosage for adults is one tablet taken orally once a day, with or without food.

Complete the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve before the treatment is finished. If you have any questions about the dosage or administration of this medication, consult your healthcare provider or pharmacist.

Mechanism of Action

Itraconol TR works by inhibiting the growth and replication of fungi. Itraconazole and Terbinafine, the active ingredients in this medication, work in slightly different ways to target different aspects of fungal cell function. Itraconazole interferes with the synthesis of ergosterol, an essential component of the fungal cell membrane, while Terbinafine disrupts the production of an enzyme called squalene epoxidase, which is necessary for the synthesis of fungal cell membranes.

By targeting these key components, Itraconol TR helps to eliminate the fungal infection and prevent its recurrence.

Side Effects

Common side effects may include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Skin rash
• Taste disturbances

If any of these side effects persist or worsen. Inform your healthcare provider. Additionally, some individuals may experience more serious side effects, such as liver problems or allergic reactions. If you experience any unusual symptoms, such as yellowing of the skin or eyes, dark urine, persistent nausea or vomiting, or difficulty breathing, seek immediate medical attention.

Drug Interactions

Itraconol TR may interact with other medications, potentially affecting their efficacy or increasing the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

Some common drug interactions with Itraconol TR include:

• Rifampin, rifabutin, or rifapentine (antibiotics)
• Phenobarbital, phenytoin, or carbamazepine (anti-seizure medications)
• Ciclosporin (immunosuppressant)
• Warfarin (blood thinner)

These are not the only potential drug interactions, so discuss your medication history with your healthcare provider to ensure the safe and effective use of Itraconol TR.

Precautions

Before starting treatment with Itraconol TR, inform your healthcare provider about any known allergies or sensitivities you may have, as well as any medical conditions you have or medications you are currently taking. This is especially important if you have liver or kidney disease, as Itraconol TR may require dose adjustments or closer monitoring in these cases.

Itraconol TR should not be used by pregnant or breastfeeding women unless specifically instructed by a healthcare provider. Use effective contraception during treatment to avoid pregnancy.

Storage

Itraconol TR should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use Itraconol TR after the expiration date printed on the packaging.

Patient Tips

• Take the medication exactly as prescribed by your healthcare provider.
• If you forget to take a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not take more than the prescribed dose of Itraconol TR.
• Avoid consuming alcohol while taking this medication, as it may increase the risk of liver problems.
• If you experience any unusual symptoms or side effects, contact your healthcare provider immediately.
• Complete the full course of treatment, even if your symptoms improve before the treatment is finished.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Terbinafine: a medicine to treat fungal skin infections (NHS UK) [Accessed 16 Jun. 2024] (online) Available at:
• Itraconazole 10 mg/ml Concentrate and Solvent for Solution for Infusion (Health Professionals SmPC) Available at:
• Itraconazole (Drugs.com) [Accessed 9 Jun. 2024] (online) Available at:
• itraconazole (RX) [Accessed 4 Jun. 2024] (online) Available at:
• Itraconazole (MedlinePlus) [Accessed 26 Jun. 2024] (online) Available at:
• Piérard GE, Arrese JE, Piérard-Franchimont C. Itraconazole. Expert Opin Pharmacother. 2000 Jan;1(2):287-304. doi: 10.1517/14656566.1.2.287. [Accessed 25 Jun. 2024] Available at: