Jakauto Ointment

Introduction

Jakauto is a topical medication that contains the active ingredient Tofacitinib. It is available in the form of an ointment and is used for the treatment of certain skin conditions.

Uses

Jakauto is prescribed for the management of moderate to severe plaque psoriasis. It is indicated for use in patients who have not responded well to other treatments or who cannot tolerate other systemic therapies.

Dosage and Administration

The recommended dosage of Jakauto is to apply a thin layer to the affected skin areas twice daily, in the morning and evening. Gently rub the ointment into the skin until it is fully absorbed. Follow the instructions provided by your healthcare professional and not exceed the recommended dosage.

Mechanism of Action

Tofacitinib, the active ingredient in Jakauto, belongs to a class of medications known as Janus kinase (JAK) inhibitors. It works by inhibiting specific enzymes in the body that are involved in the inflammatory process. By reducing inflammation, it helps to alleviate the symptoms of plaque psoriasis.

Side Effects

Common side effects may include redness, itching, burning, or stinging at the application site. These side effects are usually mild and tend to resolve on their own.

However, if you experience any serious side effects such as severe skin irritation, rash, or signs of an allergic reaction (e.g., difficulty breathing, swelling of the face or throat), seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all medications, including over-the-counter drugs and herbal supplements, that you are currently taking. Some medications may interact with Tofacitinib, potentially affecting its effectiveness or increasing the risk of side effects. Common drug interactions may include certain immunosuppressant medications or live vaccines. Your healthcare professional will be able to provide you with specific guidance based on your individual circumstances.

Precautions

Before using Jakauto, inform your healthcare professional about any known allergies or sensitivities to medications. Additionally, discuss your medical history, including any skin infections or other skin conditions.

Jakauto should not be used by individuals who have an active infection in the treatment area. Avoid contact with the eyes, mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with water.

Storage

Patient Tips

• Follow the prescribed dosage and application instructions provided by your healthcare professional.
• Avoid applying the ointment to healthy or unaffected skin areas.
• It may take some time for the full effects of Jakauto to be seen. Be patient and continue using the medication as directed.
• If you have any questions or concerns about the medication, don’t hesitate to reach out to your healthcare professional for guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• XELJANZ 1 mg/mL oral solution (Health Professionals SmPC) Available at:
• Tofacitinib (Drugs.com) [Accessed 30 Jun. 2024] (online) Available at:
• tofacitinib tablet (RX) [Accessed 0 Jun. 2024] (online) Available at:
• Tofacitinib (MedlinePlus) [Accessed 17 Jun. 2024] (online) Available at:
• Sandborn WJ, Su C, Sands BE, D’Haens GR, Vermeire S, Schreiber S, Danese S, Feagan BG, Reinisch W, Niezychowski W, Friedman G, Lawendy N, Yu D, Woodworth D, Mukherjee A, Zhang H, Healey P, Panés J; OCTAVE Induction 1, OCTAVE Induction 2, and OCTAVE Sustain Investigators. Tofacitinib as Induction and Maintenance Therapy for Ulcerative Colitis. N Engl J Med. 2017 May 4;376(18):1723-1736. doi: 10.1056/NEJMoa1606910. [Accessed 8 Jun. 2024] Available at: