Javaglip-MS 50/500 Tablet

Introduction

Javaglip-MS is a prescription medication that contains two active ingredients: Sitagliptin and Metformin. Sitagliptin is a medication in the class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors, while Metformin belongs to the class of drugs called biguanides. Javaglip-MS is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus.

Uses

Javaglip-MS is prescribed to help control blood sugar levels in adults with type 2 diabetes mellitus. It is used as an adjunct to diet and exercise to improve glycemic control. This medication is not intended for the treatment of type 1 diabetes or diabetic ketoacidosis.

Dosage and Administration

The dosage of Javaglip-MS will vary depending on individual patient factors and the specific recommendations of the prescribing healthcare professional. Follow the prescribed dosage instructions provided by your healthcare provider. Usually, the starting dose is one tablet taken orally once daily with meals. Your healthcare provider may adjust the dose as necessary to achieve optimal blood sugar control.

Mechanism of Action

Sitagliptin, one of the active ingredients in Javaglip-MS, works by inhibiting the enzyme DPP-4, which is responsible for the breakdown of incretin hormones. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones help regulate blood sugar levels by stimulating insulin release and reducing the production of glucose by the liver.

Metformin, the other active ingredient in Javaglip-MS, works by reducing the production of glucose by the liver and improving the body’s response to insulin. It also helps to decrease the absorption of glucose from the intestines.

Side Effects

Common side effects may include nausea, diarrhea, stomach upset, and headache. These side effects are usually mild and go away on their own. However, if these side effects persist or worsen, consult your healthcare provider.

In rare cases, Javaglip-MS may cause more serious side effects, such as lactic acidosis (a buildup of lactic acid in the blood), allergic reactions, or pancreatitis (inflammation of the pancreas). If you experience symptoms such as unusual tiredness, severe stomach pain, difficulty breathing, or a rash, seek immediate medical attention.

Drug Interactions

Javaglip-MS may interact with other medications, including certain antibiotics, antifungal drugs, and medications that affect the kidneys. Inform your healthcare provider about all the medications, supplements, and herbal products you are taking before starting Javaglip-MS. They can determine if any potential drug interactions exist and make appropriate adjustments to your medication regimen.

Precautions

Before taking Javaglip-MS, inform your healthcare provider of any medical conditions you have, especially if you have a history of kidney problems, liver disease, heart failure, or pancreatitis. Disclose any allergies you may have to medications or other substances.

Javaglip-MS should be used with caution in individuals with a history of lactic acidosis or who are at risk of developing it. Follow the dosage instructions and closely monitor your blood sugar levels while taking this medication.

Storage

Javaglip-MS should be stored at room temperature, away from moisture and heat. Keep the medication out of the reach of children and pets. Do not use Javaglip-MS if the expiration date has passed. If you have any unused or expired medication, consult with your pharmacist or healthcare provider for proper disposal.

Patient Tips

• Take Javaglip-MS exactly as prescribed by your healthcare provider. Do not change the dose or stop taking the medication without consulting your healthcare provider.
• maintain a healthy lifestyle, including a balanced diet and regular exercise, while taking Javaglip-MS.
• Monitor your blood sugar levels regularly as directed by your healthcare provider.
• If you experience any unusual or persistent symptoms while taking Javaglip-MS, such as severe stomach pain, difficulty breathing, or a rash, seek medical attention immediately.
• Keep all scheduled appointments with your healthcare provider for regular check-ups and blood tests to monitor your response to the medication.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Metformin: a medicine to treat type 2 diabetes (NHS UK) [Accessed 10 Jun. 2024] (online) Available at:
• Competact 15 mg/850 mg film-coated tablets (Health Professionals SmPC) Available at:
• Metformin (Drugs.com) [Accessed 6 Jun. 2024] (online) Available at:
• metformin (RX) [Accessed 21 Jun. 2024] (online) Available at:
• Metformin (MedlinePlus) [Accessed 2 Jun. 2024] (online) Available at:
• LaMoia TE, Shulman GI. Cellular and Molecular Mechanisms of Metformin Action. Endocr Rev. 2021 Jan 28;42(1):77-96. doi: 10.1210/endrev/bnaa023. [Accessed 21 Jun. 2024] Available at: