Jusgo MR 50mg/325mg/2mg Tablet

Introduction

Jusgo MR is a prescription medication that combines three active ingredients: Diclofenac, Paracetamol, and Tizanidine. It is commonly used to provide relief from pain and inflammation associated with conditions such as arthritis, muscle spasms, and other musculoskeletal disorders.

Uses

Jusgo MR is prescribed to manage pain and reduce inflammation caused by various conditions, including:

• Arthritis: This medication can help alleviate the pain and swelling associated with different forms of arthritis, such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
• Muscle Spasms: Jusgo MR is effective in relieving muscle spasms, which can occur due to injuries, strains, or underlying medical conditions.
• Musculoskeletal Disorders: It is also used to treat pain and inflammation related to musculoskeletal disorders, including tendonitis, bursitis, and fibromyalgia.

Dosage and Administration

The recommended dosage of Jusgo MR may vary depending on the severity of the condition and individual patient factors. Follow the instructions provided by your healthcare provider. Generally, the usual dosage for adults is one tablet taken orally, with or without food, two to three times a day. The tablet should be swallowed whole with a glass of water.

Not exceed the prescribed dosage or take this medication for longer than recommended, as it may increase the risk of side effects. If you have any questions or concerns regarding the dosage, consult your healthcare provider or pharmacist.

Mechanism of Action

Jusgo MR combines three active ingredients with different mechanisms of action to provide effective pain relief:

• Diclofenac: It belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Diclofenac works by inhibiting the production of substances in the body that cause pain and inflammation, known as prostaglandins.
• Paracetamol: It is a commonly used analgesic (pain reliever) and antipyretic (reduces fever). Paracetamol works by inhibiting the production of certain chemicals in the brain that transmit pain signals and regulate body temperature.
• Tizanidine: It is a muscle relaxant that acts on the central nervous system. Tizanidine works by reducing muscle spasms and increasing muscle tone, thereby providing relief from muscle-related pain and discomfort.

Side Effects

be aware of these potential side effects and seek medical attention if they occur or worsen. Common side effects may include:

• Nausea or vomiting
• Upset stomach or indigestion
• Headache
• Dizziness or drowsiness
• Skin rash or itching

In rare cases, Jusgo MR may cause more serious side effects. If you experience any of the following symptoms, contact your healthcare provider immediately:

• Severe allergic reactions, such as swelling of the face, lips, tongue, or throat
• Difficulty breathing or tightness in the chest
• Signs of liver or kidney problems, such as yellowing of the skin or eyes, dark urine, or persistent abdominal pain
• Unusual bleeding or bruising
• Changes in vision or hearing

Drug Interactions

Jusgo MR may interact with certain medications, which can affect their effectiveness or increase the risk of side effects. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some common drug interactions to be aware of include:

• Blood-thinning medications, such as warfarin
• Antidepressants or sedatives
• Blood pressure medications
• Diuretics
• Lithium

This is not an exhaustive list, so always consult your healthcare provider or pharmacist for a comprehensive review of potential drug interactions.

Precautions

Before taking Jusgo MR, consider certain precautions:

• Allergies: Inform your healthcare provider if you have any known allergies to Diclofenac, Paracetamol, Tizanidine, or any other medications.
• Medical Conditions: Discuss your medical history with your healthcare provider, especially if you have a history of liver or kidney problems, gastrointestinal disorders, high blood pressure, or heart disease.
• Pregnancy and Breastfeeding: inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They will assess the potential risks and benefits of using this medication during these periods.
• Other Medications: As mentioned earlier, inform your healthcare provider about all other medications you are taking to avoid potential drug interactions.

Storage

Jusgo MR should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets. Do not use this medication if it has expired or if the packaging is damaged.

Patient Tips

• Follow the prescribed dosage and schedule as directed by your healthcare provider.
• If you experience any unusual or severe side effects, contact your healthcare provider immediately.
• Do not consume alcohol while taking Jusgo MR, as it may increase the risk of side effects.
• Inform your healthcare provider about any other medications or supplements you are taking to avoid potential drug interactions.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.
• Store the medication in its original packaging and keep it out of reach of children.
• If you have any questions or concerns about your treatment, do not hesitate to consult your healthcare provider or pharmacist.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Diclofenac: a non-steroidal anti-inflammatory drug (NSAID) for pain and swelling (NHS UK) [Accessed 0 Jun. 2024] (online) Available at:
• Diclofenac 2.32% gel (Health Professionals SmPC) Available at:
• Diclofenac (Drugs.com) [Accessed 28 Jun. 2024] (online) Available at:
• aleve (diclofenac) 1 % topical gel non-steroidal anti-inflammatory agents (nsaid) (OTC) [Accessed 20 Jun. 2024] (online) Available at:
• Diclofenac Topical (arthritis pain) [Accessed 5 Jun. 2024] (online) Available at:
• Hamed R, Mahmoud NN, Alnadi SH, Alkilani AZ, Hussein G. Diclofenac diethylamine nanosystems-loaded bigels for topical delivery: development, rheological characterization, and release studies. Drug Dev Ind Pharm. 2020 Oct;46(10):1705-1715. doi: 10.1080/03639045.2020.1820038. Epub 2020 Sep 18. [Accessed 23 Jun. 2024] Available at: