Kelfer 250 Capsule

Introduction

Kelfer is a prescription medication that contains the active ingredient Deferiprone. It is commonly prescribed under the brand name Kelfer. This medication is primarily used for the treatment of iron overload in patients with thalassemia major, a genetic blood disorder that leads to excessive iron accumulation in the body.

Uses

Kelfer is prescribed to manage iron overload in patients with thalassemia major. Thalassemia major is a condition in which the body produces insufficient amounts of hemoglobin, the protein responsible for carrying oxygen in the blood. Due to ineffective red blood cell production, individuals with thalassemia major require frequent blood transfusions, which can lead to excess iron accumulation. Kelfer helps to reduce the levels of iron in the body, thereby preventing iron-related complications.

Dosage and Administration

The dosage of Kelfer may vary depending on individual patient characteristics and should be determined by a healthcare professional. It is typically taken orally, with or without food. The capsules should be swallowed whole and not crushed or chewed. Follow the prescribed dosage and administration instructions provided by your healthcare provider.

Mechanism of Action

Kelfer contains the active ingredient Deferiprone, which belongs to a class of medications known as iron chelators. Iron chelators work by binding to excess iron in the body and helping to remove it through urine and stool. By reducing the iron overload, Kelfer helps to prevent iron-related damage to organs and tissues.

Side Effects

Common side effects may include nausea, vomiting, abdominal pain, diarrhea, joint pain, and changes in taste. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, seek medical attention.

In rare cases, Kelfer may cause serious side effects, such as agranulocytosis (a decrease in certain white blood cells), liver problems, and changes in blood cell counts. If you develop symptoms such as fever, sore throat, unusual bleeding or bruising, yellowing of the skin or eyes, or dark urine, seek immediate medical attention.

Drug Interactions

Kelfer may interact with certain medications, including other iron chelators, certain antibiotics, and certain antacids. Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal products, to avoid potential drug interactions. Your healthcare provider can determine if any adjustments to your medication regimen are necessary.

Precautions

Before starting Kelfer, inform your healthcare provider about any allergies, medical conditions, or medications you are currently taking. This medication may not be suitable for individuals with certain liver or kidney problems. Avoid alcohol consumption while taking Kelfer, as it may increase the risk of liver problems.

Kelfer is not recommended for use during pregnancy unless clearly needed. Discuss the potential risks and benefits with your healthcare provider if you are pregnant or planning to become pregnant.

Storage

Kelfer should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication after the expiration date printed on the packaging. If you have any unused or expired medication, dispose of it properly according to local regulations.

Patient Tips

• Take Kelfer exactly as prescribed by your healthcare provider.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• Do not double the dose to make up for a missed dose.
• attend regular follow-up appointments with your healthcare provider to monitor your response to the medication and any potential side effects.
• If you have any questions or concerns about Kelfer, consult your healthcare provider for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Total iron-binding capacity (TIBC) and transferrin test (NHS UK) [Accessed 25 Jun. 2024] (online) Available at:
• Deferasirox Sandoz 360 mg film-coated tablets (Health Professionals SmPC) Available at:
• Carbonyl iron (Drugs.com) [Accessed 24 Jun. 2024] (online) Available at:
• carbonyl iron pediatric suspension (OTC) [Accessed 2 Jun. 2024] (online) Available at:
• Deferiprone (MedlinePlus) [Accessed 7 Jun. 2024] (online) Available at:
• Xiao Z, Zhong W, Liu X. Recent developments in electrochemical investigations into iron carbonyl complexes relevant to the iron centres of hydrogenases. Dalton Trans. 2021 Dec 20;51(1):40-47. doi: 10.1039/d1dt02705k. [Accessed 22 Jun. 2024] Available at: