Kendix 1% Cream

Introduction

Kendix is a topical medication that contains the active ingredient Bifonazole. It is available by prescription and is commonly used to treat various fungal infections of the skin, including athlete’s foot, ringworm, and jock itch.

Uses

Kendix is primarily prescribed for the treatment of fungal infections of the skin. It is effective against a wide range of fungi that can cause these infections. Some common conditions that Kendix is used to treat include athlete’s foot (tinea pedis), ringworm (tinea corporis), and jock itch (tinea cruris). It can also be used to treat fungal infections in other areas of the body as directed by your healthcare professional.

Dosage and Administration

Kendix is for external use only and should be applied to the affected area(s) of the skin as directed by your healthcare professional. Before applying the cream, make sure the affected area is clean and dry. Gently massage a thin layer of the cream into the skin until it is fully absorbed. Wash your hands after applying the cream, unless your hands are the affected area. The frequency of application and duration of treatment will depend on the specific condition being treated and the severity of the infection. Follow the instructions provided by your healthcare professional.

Mechanism of Action

Bifonazole, the active ingredient in Kendix, belongs to a class of medications called antifungals. It works by inhibiting the growth and reproduction of fungi, which helps to eliminate the fungal infection. Bifonazole disrupts the cell membranes of the fungi, leading to their death. This mechanism of action helps to relieve the symptoms of the fungal infection and promote healing of the affected skin.

Side Effects

Common side effects that may occur include mild skin irritation, such as redness, itching, or burning at the site of application. These side effects are usually temporary and should resolve on their own. However, if these side effects persist or worsen, consult your healthcare professional.

In rare cases, serious allergic reactions to Kendix may occur. Seek immediate medical attention if you experience any signs of an allergic reaction, such as difficulty breathing, swelling of the face or throat, or severe rash.

Drug Interactions

inform your healthcare professional about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. There are currently no known significant drug interactions with Kendix. However, it is always best to consult with your healthcare professional to ensure the safety and effectiveness of all your medications.

Precautions

Before using Kendix, inform your healthcare professional if you have any known allergies to bifonazole or any other antifungal medications. Additionally, discuss any medical conditions you have, especially if you have a weakened immune system or diabetes, as these conditions may require special consideration when using Kendix.

Avoid getting Kendix in contact with your eyes, nose, mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with water.

Storage

Kendix should be stored at room temperature, away from direct sunlight and moisture. Keep the cream in its original packaging and out of reach of children. Do not use the cream if it has expired or shows any signs of deterioration.

Patient Tips

• Follow the instructions provided by your healthcare professional regarding the application of Kendix. Use the cream for the full duration of treatment, even if your symptoms improve before that time.
• Avoid sharing towels, clothes, or other personal items with others to prevent the spread of the fungal infection.
• Keep the affected area clean and dry to aid in the healing process.
• If your symptoms do not improve or worsen after a few weeks of treatment, consult your healthcare professional for further evaluation and guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Bifonazole (International database) (Drugs.com) [Accessed 22 Jun. 2024] (online) Available at:
• Lackner TE, Clissold SP. Bifonazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses. Drugs. 1989 Aug;38(2):204-25. doi: 10.2165/00003495-198938020-00004. [Accessed 7 Jun. 2024] Available at:
• Huth L, Marquardt Y, Heise R, Fietkau K, Becker NH, Huth S, Baron JM. Bifonazole Exerts Anti-Inflammatory Effects in Human Three-Dimensional Skin Equivalents after UVB or Histamine Challenge. Skin Pharmacol Physiol. 2019;32(6):337-343. doi: 10.1159/000502213. Epub 2019 Sep 11. [Accessed 3 Jun. 2024] Available at:
• Taha Z, Arulanandam R, Maznyi G, Godbout E, Carter-Timofte ME, Kurmasheva N, Reinert LS, Chen A, Crupi MJF, Boulton S, Laroche G, Phan A, Rezaei R, Alluqmani N, Jirovec A, Acal A, Fekete EEF, Singaravelu R, Petryk J, Idorn M, Potts KG, Todesco H, John C, Mahoney DJ, Ilkow CS, Giguère P, Alain T, Côté M, Paludan SR, Olagnier D, Bell JC, Azad T, Diallo JS. Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen. Mol Ther. 2022 Sep 7;30(9):2998-3016. doi: 10.1016/j.ymthe.2022.04.025. Epub 2022 May 6. [Accessed 2 Jun. 2024] Available at: