Introduction
Keytruda is a medication that contains the active ingredient Pembrolizumab. It is available in the form of an injection and is used for the treatment of certain types of cancer.
Uses
Keytruda is prescribed to patients with advanced or metastatic melanoma, non-small cell lung cancer, head and neck squamous cell carcinoma, classical Hodgkin lymphoma, urothelial carcinoma, and gastric or gastroesophageal junction adenocarcinoma. It is also used for the treatment of patients with locally advanced or metastatic urothelial carcinoma who are not eligible for cisplatin-containing chemotherapy.
Dosage and Administration
Keytruda is administered by a healthcare professional through an intravenous infusion. The dosage and schedule may vary depending on the specific type of cancer being treated. Follow the instructions provided by the healthcare professional and not to modify the dosage or schedule without consulting them.
Mechanism of Action
Pembrolizumab, the active ingredient in Keytruda, belongs to a class of medications called immune checkpoint inhibitors. It works by blocking a specific protein called PD-1 (programmed death receptor-1) on immune cells. By blocking this protein, Pembrolizumab helps the immune system recognize and attack cancer cells.
Side Effects
Common side effects of Keytruda may include fatigue, nausea, diarrhea, decreased appetite, rash, and itching. These side effects are usually mild and temporary. However, notify your healthcare professional if any side effects persist or worsen.
Serious side effects may occur less frequently but require immediate medical attention. These can include severe allergic reactions, lung problems, liver problems, hormonal imbalances, and immune-related adverse events. If you experience any of these serious side effects, seek medical help right away.
Drug Interactions
Keytruda may interact with certain medications, including immunosuppressive agents and other immune checkpoint inhibitors. Inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal supplements, to avoid any potential drug interactions.
Precautions
Before starting treatment with Keytruda, inform your healthcare professional about any medical conditions you have, such as autoimmune disorders or previous immune-related adverse events. This medication may not be suitable for everyone, and precautions should be taken to ensure its safe use.
Keytruda may also interact with other medications or substances, such as corticosteroids or vaccines. Discuss and disclose all relevant information with your healthcare professional to avoid any potential complications.
Storage
Keytruda should be stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Keep it in the original packaging to protect it from light. If you are unsure about how to store the medication, consult your healthcare professional for guidance.
Patient Tips
- Attend all scheduled appointments with your healthcare professional for the administration of Keytruda.
- Report any side effects or changes in your condition to your healthcare professional.
- Follow a healthy lifestyle, including a balanced diet and regular exercise, to support your overall well-being.
- Keep a record of your medication schedule and any side effects you experience for discussion with your healthcare professional.
- Do not stop or modify the dosage of Keytruda without consulting your healthcare professional.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Pembrolizumab (Drugs.com) [Accessed 14 Jun. 2024] (online) Available at:
- pembrolizumab solution, reconstituted (recon soln) (RX) [Accessed 29 Jun. 2024] (online) Available at:
- Pembrolizumab Injection (MedlinePlus) [Accessed 1 Jun. 2024] (online) Available at:
- Kwok G, Yau TC, Chiu JW, Tse E, Kwong YL. Pembrolizumab (Keytruda). Hum Vaccin Immunother. 2016 Nov;12(11):2777-2789. doi: 10.1080/21645515.2016.1199310. Epub 2016 Jul 11. [Accessed 24 Jun. 2024] Available at:
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