Introduction
Kiviza, containing the active ingredient Sulbactam, is a prescription medication that is used to treat a variety of bacterial infections. It is available under the brand name Kiviza.
Uses
Kiviza is commonly prescribed for the treatment of infections caused by bacteria that are resistant to certain antibiotics. It is particularly effective against infections caused by beta-lactamase producing bacteria. Some of the common conditions treated with Kiviza include pneumonia, urinary tract infections, skin and soft tissue infections, and intra-abdominal infections.
Dosage and Administration
Kiviza should be administered under the supervision of a healthcare professional. The dosage and duration of treatment will vary depending on the specific infection and the patient’s individual factors, such as age and overall health. It is typically administered intravenously (into a vein) or intramuscularly (into a muscle). The healthcare provider will determine the appropriate dosage and frequency of administration based on the patient’s condition.
Mechanism of Action
Sulbactam, the active ingredient in Kiviza, is a beta-lactamase inhibitor. It works by inhibiting the enzymes produced by bacteria that can inactivate certain antibiotics. By inhibiting these enzymes, Sulbactam helps to restore the effectiveness of antibiotics that would otherwise be inactivated by the bacteria. This allows the antibiotics to effectively kill the bacteria and treat the infection.
Side Effects
Common side effects may include pain or redness at the injection site, nausea, vomiting, diarrhea, and headache. These side effects are usually mild and temporary.
However, if you experience any of the following serious side effects, you should seek medical attention immediately: severe allergic reactions (such as rash, itching, swelling, or difficulty breathing), severe diarrhea, or signs of liver problems (such as yellowing of the skin or eyes, dark urine, or persistent nausea).
Drug Interactions
inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal products. Some medications may interact with Kiviza, potentially affecting its effectiveness or increasing the risk of side effects. It is particularly important to avoid concurrent use of Kiviza with antibiotics that are known to be inactivated by beta-lactamase enzymes.
Precautions
Before using Kiviza, inform your healthcare provider about any allergies you may have, as well as any medical conditions you have or medications you are taking. This medication may not be suitable for everyone, and your healthcare provider will assess the potential risks and benefits before prescribing it to you.
Kiviza should not be used by individuals who are allergic to Sulbactam or any other ingredient in the medication. Follow the dosage instructions provided by your healthcare provider and not to exceed the recommended dose.
Storage
Kiviza should be stored at room temperature, away from direct sunlight and moisture. It should be kept out of the reach of children and pets. Do not use Kiviza if the packaging is damaged or if the medication has expired. Proper disposal methods should be followed as advised by your healthcare provider or local regulations.
Patient Tips
- Follow the dosage instructions provided by your healthcare provider and complete the full course of treatment, even if you start feeling better.
- If you miss a dose, contact your healthcare provider for guidance.
- Report any side effects or allergic reactions to your healthcare provider.
- Avoid using Kiviza with other medications that are known to be inactivated by beta-lactamase enzymes, unless specifically instructed by your healthcare provider.
- Store the medication as directed and dispose of any unused medication properly.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Sulbactam (International database) (Drugs.com) [Accessed 23 Jun. 2024] (online) Available at:
- ampicillin-sulbactam solution, reconstituted (recon soln) (RX) [Accessed 18 Jun. 2024] (online) Available at:
- Durlobactam Injection and Sulbactam Injection (MedlinePlus) [Accessed 21 Jun. 2024] (online) Available at:
- Keam SJ. Sulbactam/Durlobactam: First Approval. Drugs. 2023 Sep;83(13):1245-1252. doi: 10.1007/s40265-023-01920-6. [Accessed 2 Jun. 2024] Available at:
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