Kofrid 2.5 mg/30 mg/55 mg Expectorant

Introduction

Kofrid is a medication that combines three active ingredients: Chlorpheniramine Maleate, Ammonium Chloride, and Sodium Citrate. It is available in both generic form and under the brand name Kofrid. This medication is primarily used as an expectorant, which means it helps to loosen and expel mucus from the respiratory tract, making it easier to cough up.

Uses

Kofrid is commonly prescribed for the treatment of conditions that involve excessive mucus production and congestion in the respiratory system. It can be used to relieve symptoms associated with various respiratory conditions, such as the common cold, bronchitis, sinusitis, and other respiratory tract infections.

Dosage and Administration

The dosage of Kofrid may vary depending on the age, weight, and medical condition of the individual. Follow the instructions provided by your healthcare professional or the directions on the product label. Generally, the recommended dosage for adults and children over 12 years old is 10 mL (2 teaspoons) taken every 4 to 6 hours, as needed. For children aged 6 to 12 years, the recommended dosage is 5 mL (1 teaspoon) every 4 to 6 hours, as needed.

Kofrid is an oral medication and should be taken by mouth. It can be taken with or without food. Use the provided measuring device to ensure accurate dosing. Do not exceed the recommended dosage unless instructed by a healthcare professional.

Mechanism of Action

The active ingredients in Kofrid work together to help alleviate respiratory congestion and promote the clearance of mucus. Chlorpheniramine Maleate is an antihistamine that helps reduce the production of excess mucus, while Ammonium Chloride and Sodium Citrate have expectorant properties that help thin and loosen mucus in the airways, making it easier to cough up.

Side Effects

Common side effects may include drowsiness, dizziness, dry mouth, and gastrointestinal upset. These side effects are generally mild and temporary. However, if any of these side effects persist or worsen, consult a healthcare professional.

Serious side effects are rare but may include allergic reactions, difficulty breathing, rapid heartbeat, or severe dizziness. If you experience any of these serious side effects, seek immediate medical attention.

Drug Interactions

inform your healthcare professional about all the medications you are taking, including prescription, over-the-counter, and herbal products, before starting Kofrid. Certain medications may interact with Kofrid, potentially affecting its effectiveness or increasing the risk of side effects. Some common drug interactions include:

• Monoamine oxidase inhibitors (MAOIs): Taking Kofrid with MAOIs may cause serious side effects such as high blood pressure, rapid heartbeat, or seizures.
• Sedatives or tranquilizers: Combining Kofrid with these medications may increase the risk of drowsiness and central nervous system depression.
• Anticholinergic medications: Concurrent use of Kofrid with anticholinergic medications may lead to increased side effects such as dry mouth, blurred vision, and urinary retention.

Consult your healthcare professional or pharmacist for a complete list of potential drug interactions.

Precautions

Before taking Kofrid, inform your healthcare professional about any known allergies, medical conditions, or medications you are currently taking. This medication may not be suitable for individuals with certain conditions, such as glaucoma, urinary retention, high blood pressure, or heart disease. Discuss your medical history with your healthcare professional to ensure the safe use of this medication.

Kofrid may also interact with certain substances, such as alcohol or marijuana, and may increase the risk of side effects. Avoid consuming alcohol or using marijuana while taking this medication.

Storage

Kofrid should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use this medication if it has expired or if the liquid has changed in color or consistency. Properly discard any unused medication.

Patient Tips

• Follow the dosage instructions provided by your healthcare professional or the product label.
• Use the provided measuring device to ensure accurate dosing.
• If you experience drowsiness while taking Kofrid, avoid activities that require alertness, such as driving or operating machinery.
• Stay hydrated by drinking plenty of fluids to help thin and loosen mucus.
• If your symptoms persist or worsen despite taking Kofrid, contact your healthcare professional for further evaluation.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Vitamins and minerals – Others (NHS UK) [Accessed 18 Jun. 2024] (online) Available at:
• Boots Cystitis Relief (Cranberry) (Health Professionals SmPC) Available at:
• Ammonium Chloride (Drugs.com) [Accessed 16 Jun. 2024] (online) Available at:
• chlorpheniramine maleate (OTC) [Accessed 11 Jun. 2024] (online) Available at:
• Acid loading test (pH) [Accessed 16 Jun. 2024] (online) Available at:
• [No authors listed] Ammonium chloride acidosis. Br Med J. 1961 Aug 12;2(5249):441. [Accessed 3 Jun. 2024] Available at: