Introduction
Kyprolis is a prescription medication that contains the active ingredient Carfilzomib. It is available in the form of an injection and is used for the treatment of certain types of cancer.
Uses
Kyprolis is primarily prescribed for the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow. It is used in combination with other medications to help slow down the growth and spread of cancer cells.
Dosage and Administration
Kyprolis should be administered under the supervision of a healthcare professional. The dosage and administration schedule may vary depending on the individual patient and the specific treatment plan. Follow the instructions provided by your healthcare provider.
Mechanism of Action
Carfilzomib, the active ingredient in Kyprolis, belongs to a class of medications known as proteasome inhibitors. It works by blocking the activity of proteasomes, which are enzymes responsible for breaking down proteins in cells. By inhibiting proteasomes, Carfilzomib helps to prevent the growth and survival of cancer cells.
Side Effects
Common side effects may include fatigue, nausea, diarrhea, constipation, low blood cell counts, and peripheral neuropathy (nerve damage that can cause numbness or tingling in the hands and feet). Report any side effects to your healthcare provider.
Serious side effects may include heart problems, lung problems, liver problems, kidney problems, and blood clotting disorders. If you experience any severe or persistent side effects, seek immediate medical attention.
Drug Interactions
Kyprolis may interact with other medications, including but not limited to blood thinners, certain antibiotics, antifungal medications, and certain herbal supplements. Inform your healthcare provider about all the medications and supplements you are taking before starting Kyprolis.
Precautions
Before using Kyprolis, inform your healthcare provider about any pre-existing medical conditions, including heart problems, lung problems, liver problems, kidney problems, or any allergies you may have. This medication may not be suitable for everyone, and your healthcare provider will determine if it is appropriate for you.
Kyprolis should not be used during pregnancy or breastfeeding, as it may harm the unborn baby or pass into breast milk. Discuss the potential risks and benefits with your healthcare provider.
Storage
Kyprolis should be stored as directed by your healthcare provider or as indicated on the packaging. It is typically stored in a refrigerator between 2°C and 8°C (36°F and 46°F). Do not freeze the medication. Keep it away from light and moisture.
Patient Tips
- Follow the dosage and administration instructions provided by your healthcare provider.
- Report any side effects to your healthcare provider, even if they seem minor.
- Keep all appointments with your healthcare provider for regular check-ups and monitoring.
- Store Kyprolis as directed to ensure its effectiveness and safety.
- Inform your healthcare provider about all the medications and supplements you are taking.
- If you have any questions or concerns about Kyprolis, don’t hesitate to ask your healthcare provider for clarification.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Carfilzomib (Drugs.com) [Accessed 21 Jun. 2024] (online) Available at:
- carfilzomib solution, reconstituted (recon soln) (RX) [Accessed 9 Jun. 2024] (online) Available at:
- Carfilzomib Injection (MedlinePlus) [Accessed 16 Jun. 2024] (online) Available at:
- Moreau P, Dimopoulos MA, Mikhael J, Yong K, Capra M, Facon T, Hajek R, Špička I, Baker R, Kim K, Martinez G, Min CK, Pour L, Leleu X, Oriol A, Koh Y, Suzuki K, Risse ML, Asset G, Macé S, Martin T; IKEMA study group. Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial. Lancet. 2021 Jun 19;397(10292):2361-2371. doi: 10.1016/S0140-6736(21)00592-4. Epub 2021 Jun 4. [Accessed 21 Jun. 2024] Available at:
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