Introduction
Lapatem is a prescription medication that contains the active ingredient Lapatinib. It is available under the brand name Lapatem. This medication is primarily used for the treatment of certain types of breast cancer.
Uses
Lapatem is prescribed to patients with advanced or metastatic breast cancer that overexpresses the human epidermal growth factor receptor 2 (HER2). It is typically used in combination with other anticancer medications to target the specific HER2 protein and slow down the growth and spread of cancer cells.
Dosage and Administration
The dosage and administration of Lapatem should be determined by a healthcare professional based on various factors, including the patient’s overall health, the stage of cancer, and other treatments being used. Follow the prescribed dosage instructions carefully.
Lapatem is usually taken orally, with or without food. It is typically taken once a day, but the specific dosage may vary depending on individual patient needs. The tablet should be swallowed whole with a glass of water and should not be crushed, chewed, or broken.
Mechanism of Action
Lapatinib, the active ingredient in Lapatem, belongs to a class of medications known as tyrosine kinase inhibitors. It works by blocking the activity of certain proteins in cancer cells, specifically the HER2 and epidermal growth factor receptor (EGFR) proteins. By inhibiting these proteins, Lapatem helps to slow down the growth and division of cancer cells, thereby reducing the progression of breast cancer.
Side Effects
Common side effects of Lapatinib include nausea, vomiting, diarrhea, fatigue, rash, and hand-foot syndrome. These side effects are usually mild to moderate and should be reported to a healthcare professional if they persist or worsen.
In some cases, Lapatem may cause more serious side effects, such as liver problems, lung problems, or heart problems. Seek immediate medical attention if you experience symptoms such as yellowing of the skin or eyes, severe shortness of breath, or chest pain while taking this medication.
Drug Interactions
Lapatem may interact with other medications, including certain antibiotics, antifungal drugs, and medications that affect liver enzymes. Inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid any potential drug interactions.
Precautions
Before starting Lapatem, inform your healthcare provider about any medical conditions you have, especially liver problems, heart problems, or lung problems. This medication may not be suitable for everyone, and your healthcare provider will consider your overall health and medical history before prescribing it.
Lapatem should not be used during pregnancy or breastfeeding, as it may harm the developing fetus or nursing baby. Use effective contraception during treatment with this medication.
Storage
Lapatem should be stored at room temperature, away from direct sunlight and moisture. It should be kept in its original packaging and out of reach of children and pets. Do not use this medication if it has expired or if the packaging is damaged.
Patient Tips
- Take Lapatem exactly as prescribed by your healthcare provider.
- If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
- Do not double the dose to make up for a missed one.
- attend all scheduled appointments with your healthcare provider for monitoring and follow-up.
- If you have any concerns or questions about Lapatem or its potential side effects, don’t hesitate to reach out to your healthcare provider for guidance and support.
Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.
References
- Mastocytosis – Treatment (NHS UK) [Accessed 23 Jun. 2024] (online) Available at:
- Lapatinib (Drugs.com) [Accessed 15 Jun. 2024] (online) Available at:
- lapatinib 250 mg tablet antineoplastic – protein-tyrosine kinase inhibitors (RX) [Accessed 12 Jun. 2024] (online) Available at:
- Lapatinib (MedlinePlus) [Accessed 12 Jun. 2024] (online) Available at:
- Voigtlaender M, Schneider-Merck T, Trepel M. Lapatinib. Recent Results Cancer Res. 2018;211:19-44. doi: 10.1007/978-3-319-91442-8_2. [Accessed 22 Jun. 2024] Available at:
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