Lasinone 10mg Capsule

Introduction

Lasinone is a medication that contains the active ingredient Nitisinone. It is available in capsule form and is used for the treatment of a specific inherited disorder called hereditary tyrosinemia type 1 (HT-1). Lasinone is a brand name for Nitisinone.

Uses

Lasinone is prescribed for the management of hereditary tyrosinemia type 1 (HT-1), a rare genetic condition that affects the body’s ability to break down the amino acid tyrosine. This medication helps to reduce the levels of tyrosine and its byproducts in the body, which can help prevent serious health complications associated with HT-1.

Dosage and Administration

The dosage of Lasinone may vary depending on several factors, including the patient’s age, weight, and overall health condition. Follow the instructions provided by your healthcare professional. Typically, the recommended starting dose for adults and children is 1 mg/kg of body weight per day, divided into two doses. Your healthcare provider will determine the specific dosage that is appropriate for you or your child.

Lasinone should be taken orally with a glass of water, preferably with or after a meal. Do not crush or chew the capsules; swallow them whole.

Mechanism of Action

Nitisinone, the active ingredient in Lasinone, works by inhibiting the enzyme responsible for the breakdown of tyrosine in the body. By reducing the breakdown of tyrosine, this medication helps to lower the levels of toxic byproducts that can accumulate in individuals with HT-1. This mechanism of action helps to prevent or minimize the development of serious complications associated with HT-1.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, stomach pain, and headache. These side effects are generally mild and temporary. However, if any of these side effects persist or worsen, consult your healthcare provider.

In rare cases, Lasinone may cause serious side effects, such as liver problems or an allergic reaction. Seek immediate medical attention if you experience symptoms such as yellowing of the skin or eyes, dark urine, persistent nausea or vomiting, severe stomach pain, rash, itching, or swelling.

Drug Interactions

inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements. Certain medications may interact with Lasinone, potentially affecting its effectiveness or increasing the risk of side effects. Your healthcare provider will consider these potential interactions and adjust your treatment plan accordingly. Follow their guidance and inform them of any changes in your medication regimen.

Precautions

Before taking Lasinone, inform your healthcare provider about any existing medical conditions, allergies, or history of liver problems. This medication may not be suitable for individuals with certain liver conditions. Additionally, avoid excessive consumption of foods or supplements high in tyrosine, as this may interfere with the effectiveness of Lasinone.

Lasinone may also interact with certain medications, including anticoagulants and certain antifungal drugs. Your healthcare provider will assess the potential risks and benefits of using Lasinone in combination with other medications.

Storage

Store Lasinone at room temperature, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged. Follow any additional storage instructions provided by your healthcare provider or on the product packaging.

Patient Tips

• Take Lasinone exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking the medication without consulting them first.
• If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
• attend regular follow-up appointments with your healthcare provider to monitor your response to the medication and make any necessary adjustments to your treatment plan.
• If you have any questions or concerns about Lasinone or your treatment, do not hesitate to reach out to your healthcare provider. They are there to provide support and guidance throughout your treatment journey.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Nitisinone 10mg hard capsules (Health Professionals SmPC) Available at:
• Nitisinone (Drugs.com) [Accessed 17 Jun. 2024] (online) Available at:
• nitisinone 10 mg capsule drugs to treat hereditary tyrosinemia (RX) [Accessed 2 Jun. 2024] (online) Available at:
• Alkaptonuria (MedlinePlus) [Accessed 26 Jun. 2024] (online) Available at:
• [No authors listed] Nitisinone. 2022 Mar 21. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. [Accessed 22 Jun. 2024] Available at: