Lifexone 250mg Tablet

Introduction

Lifexone is a medication that contains the active ingredient Disulfiram. It is available in tablet form and is prescribed to patients for various conditions.

Uses

Lifexone is primarily used in the treatment of alcohol dependence. It is often recommended as part of a comprehensive treatment plan that includes counseling and support. This medication helps to discourage alcohol consumption by causing unpleasant reactions when alcohol is consumed.

Dosage and Administration

The dosage of Lifexone can vary depending on the individual’s specific needs and response to the medication. Follow the instructions provided by your healthcare provider. Typically, the initial dose is 500 mg once daily, which may be increased to 1,000 mg after one to two weeks. The tablets should be swallowed whole with a glass of water.

Mechanism of Action

Lifexone works by inhibiting an enzyme called aldehyde dehydrogenase, which is involved in the breakdown of alcohol in the body. This leads to an accumulation of a toxic substance called acetaldehyde when alcohol is consumed. The presence of acetaldehyde causes unpleasant symptoms such as facial flushing, nausea, and vomiting, discouraging further alcohol consumption.

Side Effects

Common side effects may include drowsiness, fatigue, headache, and metallic or garlic-like taste in the mouth. These side effects are usually mild and go away on their own. However, if you experience any severe or persistent side effects, consult your healthcare provider.

Serious side effects of Lifexone are rare but can include liver problems, such as hepatitis or liver failure. If you notice any signs of liver problems, such as yellowing of the skin or eyes, dark urine, or persistent abdominal pain, you should seek immediate medical attention.

Drug Interactions

Lifexone may interact with certain medications, including alcohol-containing products, certain antibiotics, anticoagulants, and certain antidepressants. Inform your healthcare provider about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid any potential drug interactions.

Precautions

There are certain precautions to consider when taking Lifexone. Avoid consuming any form of alcohol, including alcoholic beverages, as it can lead to severe reactions. Inform your healthcare provider about any medical conditions you have, especially liver disease, kidney disease, or psychiatric disorders, as they may affect the use of this medication.

Lifexone may interact with other medications or substances, so inform your healthcare provider about any other medications, supplements, or substances you are using.

Storage

Lifexone should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the tablets appear discolored or damaged.

Patient Tips

• strictly avoid any form of alcohol while taking Lifexone, as it can cause severe reactions.
• If you experience any side effects, such as drowsiness or fatigue, avoid activities that require mental alertness, such as driving or operating machinery.
• Be sure to follow the dosage instructions provided by your healthcare provider and do not adjust the dose without consulting them.
• Inform your healthcare provider about any other medications, supplements, or substances you are using to avoid potential drug interactions.
• If you have any questions or concerns about Lifexone, do not hesitate to consult your healthcare provider for further guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Disulfiram (Drugs.com) [Accessed 3 Jun. 2024] (online) Available at:
• disulfiram (RX) [Accessed 5 Jun. 2024] (online) Available at:
• Disulfiram (MedlinePlus) [Accessed 10 Jun. 2024] (online) Available at:
• Lei Y, Tang L, Chen Q, Wu L, He W, Tu D, Wang S, Chen Y, Liu S, Xie Z, Wei H, Yang S, Tang B. Disulfiram ameliorates nonalcoholic steatohepatitis by modulating the gut microbiota and bile acid metabolism. Nat Commun. 2022 Nov 11;13(1):6862. doi: 10.1038/s41467-022-34671-1. [Accessed 22 Jun. 2024] Available at: