Linares-E Tablet

Introduction

Linares-E is a prescription medication that contains two active ingredients: Empagliflozin and Linagliptin. Empagliflozin belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors, while Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. This combination medication is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus.

Uses

Linares-E is prescribed to help control blood sugar levels in adults with type 2 diabetes mellitus. It is used as an adjunct to diet and exercise to improve glycemic control. This medication can be used alone or in combination with other diabetes medications, such as metformin, sulfonylureas, or insulin.

Dosage and Administration

The recommended dosage of Linares-E may vary depending on individual patient factors, such as their current diabetes treatment regimen and overall health. Follow the instructions provided by your healthcare provider. Generally, the usual starting dose is one tablet taken orally once daily. The tablet should be swallowed whole with a glass of water, with or without food.

Mechanism of Action

Linares-E works by targeting different mechanisms in the body to help improve blood sugar control. Empagliflozin works by inhibiting SGLT2 in the kidneys, which reduces the reabsorption of glucose and leads to increased urinary glucose excretion. This helps lower blood sugar levels. Linagliptin, on the other hand, works by inhibiting DPP-4, an enzyme that breaks down certain hormones involved in glucose regulation. By inhibiting DPP-4, Linagliptin helps increase the levels of these hormones, which in turn helps lower blood sugar levels.

Side Effects

Common side effects may include urinary tract infections, increased urination, genital yeast infections, and flu-like symptoms. These side effects are usually mild and tend to resolve on their own.

However, be aware of more serious side effects that may require medical attention. These can include signs of allergic reactions, such as rash, itching, swelling, severe dizziness, or trouble breathing. Additionally, symptoms such as persistent urinary tract infections, signs of kidney problems (such as changes in urine output or color), or signs of pancreatitis (such as severe abdominal pain) should be reported to a healthcare provider immediately.

If you experience any side effects while taking Linares-E, consult your healthcare provider for further evaluation and guidance.

Drug Interactions

Linares-E may interact with other medications, including prescription medications, over-the-counter drugs, and herbal supplements. Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions. Examples of medications that may interact with Linares-E include diuretics, insulin or other diabetes medications, and certain medications that affect kidney function.

Precautions

Before starting Linares-E, discuss your medical history and any underlying conditions with your healthcare provider. This medication may not be suitable for individuals with certain medical conditions, such as severe kidney problems or a history of pancreatitis.

Linares-E may also have interactions with other medications or substances. Inform your healthcare provider about all the medications, including over-the-counter drugs and herbal supplements, that you are currently taking.

Storage

Linares-E should be stored at room temperature, away from moisture and direct sunlight. Keep this medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged.

Patient Tips

• Take Linares-E exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your healthcare provider.
• maintain a healthy diet and exercise routine while taking Linares-E to optimize the management of your diabetes.
• Keep a record of your blood sugar levels and report any significant changes or concerns to your healthcare provider.
• Attend regular check-ups with your healthcare provider to monitor your progress and discuss any questions or concerns you may have.
• If you have any questions or concerns about Linares-E or its use, consult your healthcare provider for further information and guidance.

Please note that this description, as well as the other content on our website is for educational purposes only. We do not provide medical advice. For specific medical advices, diagnoses and treatment options you should consult with your doctor.

References

• Empagliflozin: a medicine to treat type 2 diabetes (NHS UK) [Accessed 21 Jun. 2024] (online) Available at:
• Glyxambi 10 mg/5 mg Film-coated Tablets (Health Professionals SmPC) Available at:
• Empagliflozin (Drugs.com) [Accessed 20 Jun. 2024] (online) Available at:
• empagliflozin 10 mg-linagliptin 5 mg-metformin er 1,000 mg tablet,24hr (RX) [Accessed 16 Jun. 2024] (online) Available at:
• Empagliflozin (MedlinePlus) [Accessed 5 Jun. 2024] (online) Available at:
• Cai C, Guo Z, Chang X, Li Z, Wu F, He J, Cao T, Wang K, Shi N, Zhou H, Toan S, Muid D, Tan Y. Empagliflozin attenuates cardiac microvascular ischemia/reperfusion through activating the AMPKalpha1/ULK1/FUNDC1/mitophagy pathway. Redox Biol. 2022 Jun;52:102288. doi: 10.1016/j.redox.2022.102288. Epub 2022 Mar 18. [Accessed 14 Jun. 2024] Available at: